Results 1 to 10 of about 97,882 (147)

Dietary trans fatty acids increase serum cholesterylester transfer protein activity in man [PDF]

Atherosclerosis, 1995
The average diet may provide some 8-10 g/day of unsaturated fatty acids with a trans double bond. Previous studies showed that dietary trans fatty acids may simultaneously raise low-density lipoprotein (LDL) cholesterol and reduce high-density lipoprotein (HDL) cholesterol.
van Tol, A., Zock, P.L., van Gent, T., Scheek, L.M., Katan, M.B.   +4 more
core   +15 more sources

A mathematical model to estimate cholesterylester transfer protein (CETP) triglycerides flux in human plasma. [PDF]

BMC Syst Biol, 2019
Cholesterylester transfer protein (CETP) modulates the composition of various lipoproteins associated with cardiovascular disease. Despite its central role in lipoprotein metabolism, its mode of action is still not fully understood. Here we present a simple way to estimate CETP-mediated lipid fluxes between different lipoprotein fractions.The model ...
Jansen M, Puetz G, Hoffmann MM, Winkler K.   +3 more
europepmc   +7 more sources

Cardiovascular risk in patients with rheumatoid arthritis: the role of cholesterylester transfer protein

Journal of Medicine in Scientific Research, 2019
Aim To detect serum level of cholesterylester transfer protein (CETP) (the enzyme involved in reverse cholesterol transport) in patients with rheumatoid arthritis (RA) and to evaluate its relation to various clinical parameters of the disease, lipid ...
Taghreed F Mohammed Mostafa, Ali M Mursi, Sherry K Abdelrahman, Emad M Elshebiny, Sahar H Quashwa, Lobna Y Ebrahim   +5 more
doaj   +4 more sources

Clinical diversity and molecular mechanism of VPS35L-associated Ritscher-Schinzel syndrome. [PDF]

J Med Genet, 2023
PURPOSE: The Retriever subunit VPS35L is the third responsible gene for Ritscher-Schinzel syndrome (RSS) after WASHC5 and CCDC22. To date, only one pair of siblings have been reported and their condition was significantly more severe than typical RSS ...
Otsuji S, Nishio Y, Tsujita M, Rio M, Huber C, Antón-Plágaro C, Mizuno S, Kawano Y, Miyatake S, Simon M, van Binsbergen E, van Jaarsveld RH, Matsumoto N, Cormier-Daire V, J Cullen P, Saitoh S, Kato K.   +16 more
europepmc   +3 more sources

Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration. [PDF]

J Lipid Res, 2017
10.1194/jlr.M073684Journal of Lipid Research5891785 ...
Cheung CMG, Gan A, Fan Q, Chee ML, Apte RS, Khor CC, Yeo I, Mathur R, Cheng CY, Wong TY, Tai ES.   +10 more
europepmc   +3 more sources

Associations Between High-Density Lipoprotein Particles and Ischemic Events by Vascular Domain, Sex, and Ethnicity: A Pooled Cohort Analysis. [PDF]

Circulation, 2020
Background: High-density lipoprotein (HDL) cholesterol concentration (HDL-C) is an established atheroprotective marker, in particular for coronary artery disease; however, HDL particle concentration (HDL-P) may better predict risk.
Singh K, Chandra A, Sperry T, Joshi PH, Khera A, Virani SS, Ballantyne CM, Otvos JD, Dullaart RPF, Gruppen EG, Connelly MA, Ayers CR, Rohatgi A.   +12 more
europepmc   +3 more sources

A multitask transfer learning framework for the prediction of virus-human protein-protein interactions [PDF]

BMC Bioinformatics 2021, 2021
Viral infections are causing significant morbidity and mortality worldwide. Understanding the interaction patterns between a particular virus and human proteins plays a crucial role in unveiling the underlying mechanism of viral infection and pathogenesis. This could further help in the prevention and treatment of virus-related diseases.
arxiv   +1 more source

The cholesteryl-ester transfer protein isoform (CETPI) and derived peptides: new targets in the study of Gram-negative sepsis

Molecular Medicine, 2022
Background Sepsis is a syndrome where the dysregulated host response to infection threatens the life of the patient. The isoform of the cholesteryl-ester transfer protein (CETPI) is synthesized in the small intestine, and it is present in human plasma ...
Eréndira G. Pérez-Hernández, Víctor De la Puente-Díaz de León, Ismael Luna-Reyes, Blanca Delgado-Coello, José Sifuentes-Osornio, Jaime Mas-Oliva   +5 more
doaj   +1 more source

Hyperalphalipoproteinemia and Beyond: The Role of HDL in Cardiovascular Diseases [PDF]

, 2021
Hyperalphalipoproteinemia (HALP) is a lipid disorder characterized by elevated plasma high-density lipoprotein cholesterol (HDL-C) levels above the 90th percentile of the distribution of HDL-C values in the general population.
Averna, Maurizio, Barbagallo, Carlo Maria, Caldarella, Rosalia, Cefalù, Angelo Baldassare, Ciaccio, Marcello, Giammanco, Antonina, Nardi, Emilio, Noto, Davide   +7 more
core   +1 more source

The Association between HDL-C and Subclinical Atherosclerosis Depends on CETP Plasma Concentration:Insights from the IMPROVE Study [PDF]

, 2021
The impact of cholesteryl ester transfer protein (CETP) on atherosclerosis is highly debated. This study aimed to investigate the associations between plasma CETP or CETP genotypes and carotid intima-media thickness (cIMT) and the influence of high ...
Alessio Ravani, Alice Bonomi, Andries Smit, Beatrice Frigerio, Bruna Gigante, Cecilia Vitali, Damiano Baldassarre, Daniela Coggi, Daniela Sansaro, Elena Tremoli, Fabrizio Veglia, Gualtiero Colombo, Kai Savonen, Laura Calabresi, Massimo Mannarino, Matteo Pirro, Mauro Amato, on behalf of the IMPROVE Study Group, Philippe Giral, Sara Simonelli, Sudhir Kurl, Vanessa Bianconi   +21 more
core   +2 more sources