Results 151 to 160 of about 746,801 (362)

Falls in hospitalized older adults and the use of fall risk-increasing drugs and anticholinergic medications in Colombia: a case‒control study

open access: yesFrontiers in Pharmacology
IntroductionIn-hospital falls are multicausal in older hospitalized patients. Drugs with anticholinergic load and psychotropic effects can increase the risk of falling.ObjectiveThis study aimed to determine the associations between fall risk-increasing ...
Manuel E. Machado-Duque   +10 more
doaj   +1 more source

Association between thyroid dysfunction and cognitive impairment in type 2 diabetes mellitus: A cross‐sectional study

open access: yesJournal of Diabetes Investigation, EarlyView.
Hypothyroidism is an independent risk factor for cognitive impairment in T2DM patients, with a progressive risk increase associated with higher TSH levels. These findings underscore the importance of integrating thyroid function evaluation into the cognitive assessment and management strategy for this patient population.
Mengmeng Zheng, Xing Zhong, Ping Zhang
wiley   +1 more source

Differential involvement of hippocampal angiotensin 1 receptors in learning and memory processes in bulbectomized rats [PDF]

open access: yes, 2016
There is conflicting evidence regarding the effect of AT1 receptor antagonists on learning and memory processes. The effects of angiotensin II and losartan administration into CA1 hippocampal area on the avoidance performance in olfactory bulbectomized ...
Belcheva, Iren   +3 more
core   +1 more source

Anticholinergic Medication Burden Scales: A Systematic Review

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Anticholinergic burden refers to the cumulative anticholinergic effect of all medications taken by an individual. Anticholinergic burden scales help identify patients at risk of anticholinergic adverse effects and guide prescribing. However, substantial variation exists between scales, with no gold standard identified.
Orla Vennard   +4 more
wiley   +1 more source

Association Between Cholinesterase Inhibitor‐Overactive Bladder Antimuscarinic Prescribing Cascade and Risk of Delirium and Falls Among Individuals Living With Dementia

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Prescribing cascades occur when cholinesterase inhibitor (ChEI)‐induced urinary incontinence is misinterpreted as a new condition, leading to overactive bladder (OAB) antimuscarinic initiation. We evaluated whether the ChEI‐OAB antimuscarinic prescribing cascade was associated with delirium or falls compared with mirabegron in older
Sarah Beth Tucker   +9 more
wiley   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer   +4 more
wiley   +1 more source

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