Results 171 to 180 of about 176,034 (239)

From diarrhoea to duodenal stricture: Contrast computed tomography and portal vein gas enhance disease staging

open access: yes
Equine Veterinary Education, Volume 38, Issue 10, Page 516-518, October 2026.
C. A. McKinney‐Aguirre, N. S. Browne
wiley   +1 more source

Thermal Stability of the Guinea Green B Solution With Substrate and Its Application for the Detection of Cholinesterase Inhibitors

open access: yesAnalysis &Sensing, Volume 6, Issue 5, September 2026.
A Guinea Green B/butyrylthiocholine iodide solution offers a simple visual colorimetric approach for detecting cholinesterase inhibitors (neostigmine, VX, and A‐234). The aqueous formulation remains practically functional after 150 days at 60 °C, whereas the phosphate‐buffered variant rapidly degrades.
Lukáš Matějovský   +1 more
wiley   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 2986-3001, September 2026.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan   +24 more
wiley   +1 more source

The central cholinergic system as a therapeutic target in Parkinson's disease. [PDF]

open access: yesJ Parkinsons Dis
Miller SJ   +4 more
europepmc   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorizin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

open access: yesBMEMat, Volume 4, Issue 3, September 2026.
We constructed a Pt‐TiO2 mesoporous nanocarrier to co‐deliver phlorizin for HCC synergistic sonodynamic‐chemoimmunotherapy. This nanoplatform targets DDX5 to remodel tumor metabolism, triggers mitochondrial damage, suppresses tumor proliferation, and elicits potent anti‐tumor immune responses by activating T cells and boosting immune cytokines in mice.
Kairui Liu   +13 more
wiley   +1 more source

Prostaglandin E2 modulates contractility of mouse bladder smooth muscle cells. [PDF]

open access: yesFront Physiol
Šumak R   +4 more
europepmc   +1 more source

Therapeutic Potential of Oxiracetam in Neurocognitive Disorders: A Narrative Review

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Purpose: Cognitive impairment is a growing global health concern associated with aging, neurodegenerative diseases, stroke, and traumatic brain injury. Existing pharmacological treatments, including cholinesterase inhibitors and memantine, provide limited and variable benefits.
Hafsa Ali   +4 more
wiley   +1 more source

Moringa oleifera Lam. Seed Lectin (WSMoL) Attenuates Parkinsonian Symptoms in Mice via Anti‐Inflammatory, Antioxidant, and Neurotransmitter‐Modulating Effects

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
WSMoL attenuates motor impairment, neuroinflammation, oxidative stress, and monoamine depletion in a rotenone‐induced model of Parkinson's disease. The involvement of D1 receptor‐mediated signaling is demonstrated, providing new insights into the mechanisms underlying its neuroprotective effects and supporting WSMoL as a promising candidate for further
Leydianne Leite de Siqueira Patriota   +14 more
wiley   +1 more source

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