Results 181 to 190 of about 746,801 (362)

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière   +6 more
wiley   +1 more source

Neurotransmitter Systems in Alzheimer's Disease. [PDF]

open access: yesCurr Issues Mol Biol
Ramírez-Expósito MJ   +2 more
europepmc   +1 more source

Influence of age and biological sex on sweating in children exercising in warm and hot environments with comparison to adults

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Local sweating response and sweating onset of boys, girls, adult females and adult males during treadmill walking at a fixed metabolic heat production per body surface area (300 W·m−2) in warm and hot environments. Bayesian hierarchical modelling showed no meaningful sex or age differences in local sweating responses or onset ...
Thomas H. Topham   +7 more
wiley   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

open access: yeseFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam   +4 more
wiley   +1 more source

Differential Neuronal Development in iPSC‐Derived Neural Stem Cells From Monozygotic Twin Cases With Treatment‐Resistant Schizophrenia and Discordant Responses to Clozapine

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
We investigated early neuronal development using iPSCs from twins with treatment‐resistant schizophrenia discordant for clozapine response. The non‐responder exhibited more pronounced impairment in differentiation than the responder. Transcriptomic analysis revealed distinct developmental gene expression profiles, suggesting that early ...
Shotaro Kawano   +13 more
wiley   +1 more source

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