Results 1 to 10 of about 3,509 (99)

Cholinergic Neuronal Deficits in CADASIL [PDF]

open access: yesStroke, 2007
Background and Purpose— Previous evidence from MRI and acetylcholinesterase histochemistry suggests cholinergic fibers are affected in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Methods—
Iryna Ziabreva   +5 more
openaire   +3 more sources

Preferential cholinergic excitation of corticopontine neurons [PDF]

open access: yesThe Journal of Physiology, 2017
Key points Phasic activation of M1 muscarinic receptors generates transient inhibition followed by longer lasting excitation in neocortical pyramidal neurons. Corticopontine neurons in the mouse prefrontal cortex exhibit weaker cholinergic inhibition, but more robust and longer lasting excitation, than neighbouring callosal projection neurons ...
Baker, Arielle L.   +2 more
openaire   +4 more sources

New Insights Into Cholinergic Neuron Diversity [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2019
Cholinergic neurons comprise a small population of cells in the striatum but have fundamental roles in fine tuning brain function, and in the etiology of neurological and psychiatric disorders such as Parkinson's disease (PD) or schizophrenia. The process of developmental cell specification underlying neuronal identity and function is an area of great ...
Noorya Yasmin Ahmed   +2 more
openaire   +4 more sources

Cholinergic Inhibition of Neocortical Pyramidal Neurons [PDF]

open access: yesThe Journal of Neuroscience, 2005
Acetylcholine (ACh) is a central neurotransmitter critical for normal cognitive function. Here we show that transient muscarinic acetylcholine receptor activation directly inhibits neocortical layer 5 pyramidal neurons. Using whole-cell and cell-attached recordings from neurons in slices of rat somatosensory cortex, we demonstrate that transient ...
Gulledge, Allan T, Stuart, Gregory J
openaire   +4 more sources

The Non-neuronal Cholinergic System

open access: yesJapanese Journal of Pharmacology, 2001
Abstract Acetylcholine (ACh) is a well characterized neurotransmitter occurring throughout the animal kingdom. In addition, both muscarinic and nicotinic ACh receptors have been identified on lymphocytes of various origin, and their stimulation by muscarinic or nicotinic agonists elicits a variety of functional and biochemical effects.
Takeshi Fujii, Koichiro Kawashima
openaire   +6 more sources

Regulation of Cholinergic Phenotype in Developing Neurons [PDF]

open access: yesJournal of Neurophysiology, 2008
Specification of neurotransmitter phenotype is critical for neural circuit development and is influenced by intrinsic and extrinsic factors. Recent findings in rat hypothalamus in vitro suggest the role of neurotransmitter glutamate in the regulation of cholinergic phenotype.
Andrei B. Belousov   +5 more
openaire   +3 more sources

Developmental specification of forebrain cholinergic neurons

open access: yesDevelopmental Biology, 2017
Striatal cholinergic interneurons and basal forebrain cholinergic projection neurons, which together comprise the forebrain cholinergic system, regulate attention, memory, reward pathways, and motor activity through the neuromodulation of multiple brain circuits.
Robert Machold, Kathryn C. Allaway
openaire   +2 more sources

Phorbol esters mimic some cholinergic actions in hippocampal pyramidal neurons [PDF]

open access: hybrid, 1986
RC Malenka   +3 more
openalex   +1 more source

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