Results 61 to 70 of about 3,509 (99)
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Acetylcholinesterase and the cholinergic neuron
Life Sciences, 1979Abstract While the distribution of AChE in the central nervous system remains largely unexplained, neurons with very high levels of AChE are frequently identified as cholinergic, and cholinergic neurons always have high levels of AChE. This supports the utility of the empirical rule, that identification of cholinergic neurons requires demonstration ...
H.C. Fibiger, John Lehmann
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Choline and Cholinergic Neurons
Science, 1983Mammalian neurons can synthesize choline by methylating phosphatidylethanolamine and hydrolyzing the resulting phosphatidylcholine. This process is stimulated by catecholamines. The phosphatidylethanolamine is synthesized in part from phosphatidylserine; hence the amino acids methionine (acting after conversion to S
Richard J. Wurtman, Jan K. Blusztajn
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The biochemistry of the cholinergic neurone [PDF]
Trends in Biochemical Sciences, 1976 The cholinergic electromotor system of the electric ray, Torpedo marmorata , provides a hypertrophied version of the normal motor nerves supplying the muscles which simplifies the biochemical study of cholinergic transmission. The mechanism of storage and release of acetylcholine from the presynaptic nerve terminal and the interaction of the ...
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Mesopontine cholinergic and non-cholinergic neurons in schizophrenia
Neuroscience, 1999Mesopontine cholinergic neurons influence midbrain dopaminergic neurons, and thalamic and cerebellar structures which have been implicated in the neuroanatomy of schizophrenia. It has been reported that there are approximately twice as many mesopontine cholinergic neurons in schizophrenics than in normals, using nicotinomide adenosine dinucleotide ...
Kebreten F. Manaye +4 more
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From the cholinergic gene locus to the cholinergic neuron
Journal of Physiology-Paris, 1998The cholinergic gene locus (CGL) was first identified in 1994 as the site (human chromosome 10q11.2) at which choline acetyltransferase and a functional vesicular acetylcholine transporter are co-localized. Here, we present recent neuroanatomical, developmental, and evolutionary insights into the chemical coding of cholinergic neurotransmission that ...
Burkhard Schütz +7 more
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The localization of central cholinergic neurons
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1986Over the past decade our understanding of the localization of central cholinergic neurons has greatly increased. Interest in these systems has also intensified due to the involvement of cholinergic mechanisms in Alzheimer's disease. The distribution of central cholinergic neurons is reviewed, focusing on recent work in experimental animals.
Keiji Satoh +2 more
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Cholinergic neurons in the human retina
Experimental Eye Research, 1987Choline acetyltransferase (ChAT)-like immunoreactivity in the human retina can be demonstrated using a polyclonal antiserum to ChAT isolated from chick brain. There is a population of ChAT-like immunoreactive cells along both margins of the inner plexiform layer (IPL).
James B. Hutchins, Joe G. Hollyfield
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The development of cholinergic neurons
Brain Research Reviews, 1988Motoneuron precursors acquire some principles of their spatial organization early in their cell lineage, probably at the blastula stage. A predisposition to the cholinergic phenotype in motoneurons and some neural crest cells is detectable at the gastrula to neurula stages. Cholinergic expression is evident upon cessation of cell division.
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Cholinergic Neurons and Cholinergic Projections in the Mammalian CNS [PDF]
, 1986 Considerable information regarding the distribution of cholinergic neurons in the mammalian central nervous system has now been accumulated. This is due to the development of reliable markers for these cells. The most significant one is immunohistochemical staining for choline acetyltransferase (ChAT), the enzyme for acetylcholine synthesis.
P. L. McGeer +3 more
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Cholinergic modulation of the cortical neuronal network
Pflügers Archiv - European Journal of Physiology, 2003Acetylcholine (ACh) is an important neurotransmitter of the CNS that binds both nicotinic and muscarinic receptors to exert its action. However, the mechanisms underlying the effects of cholinergic receptors have still not been completely elucidated.
Lucas-Meunier, Estelle +3 more
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