Results 81 to 90 of about 3,509 (99)

Biochemistry of Cholinergic Neurons

1975
The cholinergic system has not evoked the interest of psychopharmacologists to the same extent as the adrenergic or indoleaminergic systems of neurotransmission. It is not surprising that lay interest in hallucinogenesis has not included cholinergic agents such as the muscarinic drugs, because severe physiological reactions overlie their psychedelic ...
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Cholinergic neurons in the onychophora: A comparative study

Comparative Biochemistry and Physiology, 1965
Abstract 1. 1. Representative species of the phyla Arthropoda, Annelida and Onychophora were chosen for a comparison of the neurochemical organization of their nervous system. 2. 2. Onychophoran muscles were found to be cholinoceptive and, like those of annelids, to be innervated by cholinergic motor neurons.
Ernst Florey, Ernst Florey, Elisabeth Florey, Elisabeth Florey   +3 more
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Phospholipid methylation and cholinergic neurons

1982
The ability of cholinergic neurons to synthesize and release acetylcholine (ACh) depends, among other things, on their supply of choline (Ch) molecules. Several mechanisms are known to provide this choline, including the pathway described below: the de novo synthesis of phosphatidylcholine (PC) from phosphatidylethanolamine (PE), and its subsequent ...
Steven H. Zeisel, Richard J. Wurtman, Jan Krzysztof Blusztajn   +2 more
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Ontogeny of cholinergic neurons in the mouse forebrain

Journal of Comparative Neurology, 1989
AbstractThe development of cholinergic neurons in the mouse forebrain was studied by immunocytochemistry with a monoclonal antibody to choline acetyl‐transferase (ChAT), the rate‐limiting enzyme for acetylcholine synthesis. Since this antibody stained dividing cells in ventricular germinal zones as well as differentiating neurons, likely routes of ...
Kathleen K. Sulik, Uta B. Schambra, Jean M. Lauder, Peter Petrusz   +3 more
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Development of cholinergic neurons of the rat retina

Developmental Biology, 1982
Abstract Biochemical and electrophysiological features of cholinergic neurons from the developing rat retina were analyzed in an attempt to identify important periods in the maturation of these neurons. Acetylcholine synthesis was assayed in intact, isolated retinas; choline acetyltransferase activity was measured in homogenates.
Donald G. Puro, Barbara-A. Battelle, Kristin Hansmann   +2 more
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Cholinergic neurons in the rat nodose ganglia

Neuroscience Letters, 1987
Presence of acetylcholine (ACh) in the vagal afferent fibres of the rat was investigated. In the nodose ganglion, which contains the cell bodies of this sensitive contingent, a choline acetyltransferase (ChAT) activity, a choline (Ch) uptake and an endogenous content of acetylcholine were detected.
J.P. Ternaux, P. Portalier, M.C. Barrit-Chamoin, B. Palouzier   +3 more
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Antibodies to Cholinergic Neurons in Alzheimer's Disease

Journal of Neurochemistry, 1988
Abstract: Alzheimer's disease (AD) is associated with degenerative changes in nuclei of the basal forebrain which provide most of the cholinergic input to the cortex and hippocampus and with a reduction in presynaptic cholinergic parameters in these areas.
Eliyahu Wertman, Orit Bachar, Amos D. Korczyn, Joab Chapman, Daniel M. Michaelson   +4 more
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Cholinergic excitation of dendrites in neocortical neurons

Neuroscience, 1998
Discharge patterns were studied in response to iontophoretic application of acetylcholine to the soma and dendrites of 128 neocortical pyramidal neurons of layer V. Extracellular recordings were obtained from slices of the guinea-pig parietal cortex.
S.V Karnup, Yu. S. Mednikova, E. V. Loseva   +2 more
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Cholinergic neurones and memory [PDF]

Nature, 1981
Daniel K. Reinstein, Richard J. Wurtman, Steven H. Zeisel, Suzanne Corkin, John H. Growdon   +4 more
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Cholinergic neurons in tunicates: An appraisal of the evidence

Comparative Biochemistry and Physiology, 1967
Abstract 1. 1. Isolated longitudinal muscles of Ciona intestinalis contract in response to applied cholinesters. Of several esters tried, ACh is the most effective; the threshold concentration is about 10 −7 g/ml. No consistent potentiation of the ACh occurs when eserine is applied. 2. 2. The action of ACh is blocked by banthine, atropine,
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