New Sulfonate Ester-Linked Fluorinated Hydrazone Derivatives as Multitarget Carbonic Anhydrase and Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, Molecular Docking and ADME Analysis. [PDF]
Akış B, Çakmak R, Şentürk M.
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Moderation of Amyloid-β Deposition on the Effect of Cholinesterase Inhibitors on Cognition in Mild Cognitive Impairment. [PDF]
Byeon G +10 more
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A Sustainable Synthetic Approach to Tacrine and Cholinesterase Inhibitors in Deep Eutectic Solvents under Aerobic Conditions. [PDF]
Cicco L, Perna FM, Capriati V, Vitale P.
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Long-term effects of cholinesterase inhibitors and memantine on cognitive decline, cardiovascular events, and mortality in dementia with Lewy bodies: An up to 10-year follow-up study. [PDF]
Xu H +5 more
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Treating Vascular Dementia : Cholinesterase Inhibitors and …
Nagaraja D, Gangadhar B.N.
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Cholinesterase Inhibitors and Beyond
Current Alzheimer Research, 2009Cholinesterase inhibitors (ChEIs) were introduced in the therapy of Alzheimer Disease (AD) in the nineteen nineties with great expectations. The hopes and large interest raised by these drugs are well demonstrated by 12,000 references listed by PubMed under 'ChEI' for 1995-2007. The list is reduced to 2500 if we confine ourselves to 'ChEIs and dementia'
PEPEU, GIANCARLO +1 more
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Dementia is a serious and growing problem that presents enormous burdens to patients, their families, and national healthcare systems throughout the world. In the United States, there are currently two classes of psychopharmacologic agents approved for the treatment of Alzheimer's disease: the cholinesterase inhibitors, which are approved for use in ...
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Cholinesterases and Cholinesterase Inhibitors
Archives of Neurology, 20011. Introduction 2. Cholinesterase Inhibitors: An Introduction 3. Molecular Structure of Cholinesterases and Complexes with Inhibitors 4. Rational Design of Cholinesterase Inhibitors 5. Genetics and Epigenetics of Mammalian Cholinesterases 6. The Gene Structure of Cholinesterases 7. Molecular Forms and Anchoring of Cholinesterases 8. Mechanism of Action
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