Results 41 to 50 of about 2,742 (171)

ATP‐induced chondrocalcinosis [PDF]

open access: yesArthritis & Rheumatism, 1992
AbstractObjective. To determine whether adult articular cartilage mineralizes in the presence of ATP.Methods. Intact adult porcine articular cartilage and monolayers of chondrocytes were cultured in physiologic media containing ATP, and mineralization was measured as retention of 45Ca. Cartilage was analyzed by electron microscopy.Results.
L M, Ryan   +3 more
openaire   +2 more sources

Crowned Dens Syndrome Mimicking Atlantoaxial Infection in a Patient With Systemic Sclerosis: A Case Report

open access: yesCase Reports in Rheumatology, Volume 2026, Issue 1, 2026.
Objective Crowned dens syndrome (CDS), caused by calcium pyrophosphate or hydroxyapatite deposition around the odontoid process, is an under‐recognized cause of acute severe neck pain and headache. It can closely mimic septic arthritis, osteomyelitis, giant cell arteritis (GCA), polymyalgia rheumatica (PMR), or cervical spondylitis. We report a case of
Tarun Selvarajan   +4 more
wiley   +1 more source

Calcium Pyrophosphate Deposition Disease of the Temporomandibular Joint*

open access: yesJournal of Neurological Surgery Reports, 2012
Calcium pyrophosphate dihydrate deposition disease (CPDD, tophaceous pseudogout) is a rare crystal arthropathy characterized by calcium pyrophosphate crystal deposition in joint spaces, episodes of synovitis, and radiological features of ...
Vasisht Srinivasan   +5 more
doaj   +1 more source

Polyarticular and familial chondrocalcinosis [PDF]

open access: yesArthritis & Rheumatism, 1970
AbstractFrom our series of 72 patients with articular chondrocalcinosis, 37 who presented polyarticular involvement are described. Twenty‐eight patients, including 19 aggregated within different family groups, are natives of the Chiloé island group. Members of 1 of the 6 families had unusually severe disease with deformities, and 1 had bony ankylosis ...
Reginato, Antonio   +4 more
openaire   +3 more sources

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

open access: yesAdvanced Photonics Research, Volume 6, Issue 12, December 2025.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka   +5 more
wiley   +1 more source

Further Evidence That Chondrocalcinosis 1 (CCAL1) is a Confirmed Mendelian Phenotype With a Known Molecular Basis

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 12, December 2025.
ABSTRACT Chondrocalcinosis (CCAL), also known as calcium pyrophosphate dihydrate deposition disease (CPPDD), is a frequent multifactorial condition in the elderly, but there are two rare autosomal dominant Mendelian forms, CCAL1 (OMIM %600668) and CCAL2. Only three families with molecularly proven CCAL1 have been reported.
Anna‐Christina Pansa   +4 more
wiley   +1 more source

Recurrent Nephrolithiasis and Beyond: The Long Diagnostic Odyssey of a Case of CLDN16 Mutation

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis (FHHNC) is a rare tubulopathy resulting from mutations in the CLDN16 and CLDN19 genes. The affected individuals commonly present with polyuria, polydipsia, excessive urinary magnesium (Mg) and calcium (Ca) wasting, nephrocalcinosis, nephrolithiasis, recurrent urinary tract ...
Abdullah Al Noman Bhuiyan   +4 more
wiley   +1 more source

Diffuse articular chondrocalcinosis [PDF]

open access: yesEinstein (São Paulo), 2008
Chondrocalcinosis is a disease caused by joint deposition of calciumphyrophosphate dehydrate crystals, which can lead to many differentclinical presentations.
Ana Luisa Vanalle Ferrari   +1 more
doaj  

First Report of Intervertebral Disc Calcification in a Black Child in Sub‐Saharan Africa

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
Standard X‐ray of the cervical spine from the front and in profile. Blurred appearance of the C2–C3 and C3–C4 vertebral endplates and calcification (orange arrow) in the intervertebral disc of C2–C3. ABSTRACT We report an intervertebral disc calcification in a Black African child who had consulted us for neck pain. The diagnosis of C2–C3 intervertebral
Yamyelle Enselme Zongo   +7 more
wiley   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 23, September 8, 2025.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi   +10 more
wiley   +1 more source

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