Results 51 to 60 of about 2,742 (171)

Chondrocalcinosis in elderly persons [PDF]

Arthritis & Rheumatism, 1975
AbstractFifty‐eight elderly people were surveyed for chondrocalcinosis with knee, hip and pelvic roent‐genograms using Type M industrial x‐ray film. Chondrocalcinosis was found in 16 subjects (27.6%), an incidence greater than reported in previous studies. Roentgenograms of the knees alone showed the presence of chondrocalcinosis in 15 subjects.
M H, Ellman, B, Levin
openaire   +2 more sources

An effective encoding of human medical conditions in disease space provides a versatile framework for deciphering disease associations

Quantitative Biology, Volume 13, Issue 3, September 2025.
Abstract It is challenging to identify comorbidity patterns and mechanistically investigate disease associations based on health‐related data that are often sparse, large‐scale, and multimodal. Adopting a systems biology approach, embedding‐based algorithms provide a new perspective to examine diseases under a unified framework by mapping diseases into
Tianxin Xu, Yu Li, Xin Gao, Andrey Rzhetsky, Gengjie Jia   +4 more
wiley   +1 more source

Association of 4-basepair G-to-A transition in the 5′-untranslated region of ANKH gene with selected patients of primary knee osteoarthritis: A cross sectional study

Journal of Family Medicine and Primary Care, 2019
Method: A cohort study was carried out for a year to evaluate the presence of G-to-A transition in 5′-untranslated region of ankylosis human (ANKH) gene in Indian Khatri patients (closely resembling Europeans of primary knee osteoarthritis (OA), residing
Puneet Kumar, Aarti Sharma, Siddharth Das, Ragini Srivastava, Nikhil Gupta   +4 more
doaj   +1 more source

Chondrocalcinosis and Gitelman syndrome [PDF]

QJM, 2016
A 37-year-old Polish lady presented left knee pain causing reduced mobility and time off work. She also complained of intermittent episodes of fatigue. Knee X-ray showed marked chondrocalcinosis (Figure 1). Serum electrolytes revealed a potassium level of 2.8 mmol/l and magnesium of 0.46 mmol/l and a hypochloraemic metabolic alkalosis.
Z, Iqbal, J A, Sayer
openaire   +2 more sources

Novel Pathogenic Genotype in SLC12A3 Associated to Gitelman Syndrome: A Case Report

Nephrology, Volume 30, Issue 9, September 2025.
ABSTRACT Gitelman syndrome (GS) is considered one of the most common hereditary renal tubular disorders, characterised by hypokalemia, hypomagnesemia, hypocalciuria, and metabolic alkalosis. The primary cause of this disorder resides in the SLC12A3 gene, which encodes the NaCl cotransporter in the distal convoluted tubule, and for which more than 500 ...
Patricia Tomás‐Simó, Antonio Sierra‐Rivera, Ana Checa‐Ros, Raquel Rodríguez‐López, Antonio Galán‐Serrano, Luis D'Marco   +5 more
wiley   +1 more source

Change perspective to increase diagnostic accuracy of ultrasonography in calcium pyrophosphate dihydrate deposition disease! A new approach: the axial scan of the meniscus

Reumatismo, 2015
Ultrasonography (US) is a relevant tool in the study of calcium pyrophosphate dihydrate (CPP) deposition disease. However, differential diagnosis of hyperechoic deposits within the fibrocartilage can be difficult; moreover, US study is limited by the ...
G. Filippou, V. Picerno, A. Adinolfi, V. Di Sabatino, I. Bertoldi, M. Galeazzi, B. Frediani   +6 more
doaj   +1 more source

Adsorption of Proteins on m-CPPD and Urate Crystals Inhibits Crystal-Induced Cell Responses: Study on Albumin-Crystal Interaction

Journal of Functional Biomaterials, 2019
The biological effects and cellular activations triggered by monosodium urate (MSU) and calcium pyrophosphate dihydrate (monoclinic: m-CPPD) crystals might be modulated by protein coating on the crystal surface.
Felix Renaudin, Stéphanie Sarda, Laure Campillo-Gimenez, Childérick Séverac, Thibaut Léger, Cédric Charvillat, Christian Rey, Frédéric Lioté, Jean-Michel Camadro, Hang-Korng Ea, Christèle Combes   +10 more
doaj   +1 more source

Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded

MedComm, Volume 6, Issue 7, July 2025.
Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin, San‐yang Yu, Jia‐lu Gao, Jian‐fei Yan, Qian‐qian Wan, Shuai‐lin Jia, Franklin Tay, Kai Jiao, Lina Niu   +8 more
wiley   +1 more source

Lumbar Spine Pseudogout Mimicking Disc Prolapse and Radiculopathy: A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research
Calcium Pyrophosphate Dihydrate (CPPD) deposition disease, also known as pseudogout, is a crystal-induced arthropathy that primarily affects larger, weight-bearing joints such as the knees, hips, and shoulders.
Aishwarya Manish Bhaskare, Maithili Mandar Kulkarni, Shital Gosavi, Jaai Naiknavare, Siddhi Gaurish Sinai Khandeparkar   +4 more
doaj   +1 more source

Bone status and aortic calcifications in chondrocalcinosis patients

Romanian Journal of Laboratory Medicine, 2020
Aim: We aimed to examine the association between several circulating bone turnover markers [ osteocalcin (OC), osteoprotegerin (OPG), beta-CrossLaps (β-CTx)], hip and spine bone mineral density (BMD) and abdominal aortic calcification (AAC) in patients ...
Vele Paulina, Silaghi Ciprian Nicolae, Damian Laura Otilia, Simon Siao-Pin, Craciun Alexandra, Rednic Simona   +5 more
doaj   +1 more source