Results 111 to 120 of about 10,804 (272)

Anti‐PF4 disorders: Pathogenesis, diagnosis and treatment

British Journal of Haematology, EarlyView.
Anti‐platelet factor 4 (PF4) disorders include heparin‐induced thrombocytopenia (HIT) and vaccine‐induced immune thrombocytopenia and thrombosis (VITT)/VITT‐like disorders. The formation of immunoglobulin G (IgG)/PF4 immune complexes facilitates uncontrolled activation of platelets, neutrophils and monocytes via IgG‐mediated Fcγ receptor binding.
Megan V. Preece, Devi V. Pathak, Mike Laffan, Deepa J. Arachchillage   +3 more
wiley   +1 more source

Correction to “Sequential Targeting Chondroitin Sulfate‐Bilirubin Nanomedicine Attenuates Osteoarthritis via Reprogramming Lipid Metabolism in M1 Macrophages”

Advanced Science, EarlyView.
wiley   +1 more source

Engineering Intervertebral Disc Regeneration: Biomaterials, Cell Sources and Animal Models

Cell Proliferation, EarlyView.
This review highlights the current tissue engineering approaches utilising biomaterials, animal models and cell sources for intervertebral disc regeneration and discusses future opportunities. ABSTRACT Intervertebral disc (IVD) degeneration is an age‐related problem triggering chronic spinal issues, such as low back pain and IVD herniation.
Sidong Yang, Farhad Soheilmoghaddam, Peter Pivonka, Joan Li, Samuel Rudd, Trifanny Yeo, Ji Tu, Yibo Zhu, Justin J. Cooper‐White   +8 more
wiley   +1 more source

Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co‐Culture System

Cell Proliferation, EarlyView.
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai, Jiting Li, Ze Wang, Yuhan Yang, Jieqing He, Gonglie Chen, Yufan Zhang, Yan Qi, Zhongjun Wan, Lin Cai, Run Wang, Kai Wang, Dongyu Zhao, Jingzhong Zhang, Weihua Huang, Ronald X. Xu, Mingzhai Sun, Xiao Han, Yan Liu, Donghui Zhang, Wanying Zhu, Jian Liu, Yuxuan Guo   +22 more
wiley   +1 more source

Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models of epilepsy. We studied potential ECM changes in a mouse model of pilocarpine‐induced status epilepticus (PISE) and their potential contributions to
AnnaLin M. Woo, Erik J. Fleischel, Dipan C. Patel, Harald Sontheimer   +3 more
wiley   +1 more source

The O-Serine Linkage in Peptides of Chondroitin 4- or 6-Sulfate

, 1965
Bonnie Anderson, Philip Hoffman, Karl Meyer   +2 more
openalex   +1 more source

Chondroitin sulfate in invertebrate development

Proteoglycan Research
AbstractChondroitin sulfate (CS) is one of the most evolutionarily conserved glycosaminoglycans (GAGs). Although CS's function in skeletal development is well established in vertebrates, CS exists in more primitive animal species with no cartilage or bone, such as C.
Moriya, Ayano, Nakato, Eriko, Li, Jin-Ping, Nakato, Hiroshi   +3 more
openaire   +2 more sources

Equine temporomandibular joint diseases: A systematic review

Equine Veterinary Journal, EarlyView.
Abstract Background The temporomandibular joint (TMJ) is a unique joint that enables mandibular movement. Temporomandibular diseases (TMDs) impair joint function, leading to more or less specific clinical signs. Objectives To compile and disseminate clinical data and research findings from existing publications on equine TMD.
Tomasz Jasiński, Bernard Turek, Michał Kaczorowski, Walter Brehm, Katarzyna Skierbiszewska, Małgorzata Domino   +5 more
wiley   +1 more source

Structure of the Chondroitin 4-Sulfate-Protein Linkage Region

, 1966
Lennart Rodén, Gérard Armand
openalex   +1 more source

Osteochondrosis in horses: An overview of genetic and other factors

Equine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez, Pablo J. Marín‐García, M. Lola Llobat   +2 more
wiley   +1 more source