High-Value Components and Bioactives from Sea Cucumbers for Functional Foods—A Review
Sea cucumbers, belonging to the class Holothuroidea, are marine invertebrates, habitually found in the benthic areas and deep seas across the world. They have high commercial value coupled with increasing global production and trade.
Nazamid Saari +2 more
doaj +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Antibodies to Chondroitin Sulfates A, B, C: clinico-pathological correlates in neurological diseases
Anti-chondroitin sulfates (ChSs) antibodies have been reported in neuropathy and neurodegenerative diseases. Differences in specificities may account for their association with different diseases.
SANTORO M, LATOV N., BRIANI, CHIARA
core
Chondroitin 4-Sulfate Disaccharide-Based Inhibitors of Cathepsin S
Cathepsin S (Cat S) is a cysteine protease involved in several human diseases (i.e., autoimmune, inflammatory and cardiovascular disorders, cancer, and psoriasis) and is an important target in drug development.
Alexis David +11 more
doaj +1 more source
A Sweet Talk: The Molecular Systems of Perineuronal Nets in Controlling Neuronal Communication
Perineuronal nets (PNNs) are mesh-like structures, composed of a hierarchical assembly of extracellular matrix molecules in the central nervous system (CNS), ensheathing neurons and regulating plasticity.
Heleen M. van 't Spijker +2 more
doaj +1 more source
WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara +7 more
wiley +1 more source
Chondroitin sulfates are linear polysaccharides of alternating glucuronic acid and N-acetylgalactosamine, sulfated in varying positions. They form the extracellular framework providing the information for the structural establishment of tissues in ...
VOLPI, Nicola +3 more
core +1 more source
Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications
There are few reviews on hydrogel adhesives that comprehensively highlight the design principles, factors affecting adhesion, and applications for gastrointestinal (GI) perforation repair. This review outlines the mainstream design approaches of hydrogel adhesives via covalent and noncovalent molecular interactions, illustrating the underlying adhesive
Yudi Pang +7 more
wiley +1 more source
Commissural projection from the vestibular nucleus in rat embryos: role of chondroitin sulfates
To determine if chondroitin sulfates (CS) contribute restrictive guidance in commissural projections from the vestibular nucleus, we treated embryos (E12.5-14.5, Sprague-Dawley rats) with chondroitinase ABC or vehicle via the fourth ventricle for 24 hrs ...
Yuen, YL +4 more
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Preparation and Biological Activity of N-Sulfated Chondroitin and Dermatan Sulfate Derivatives
Carbohydrate Research, 290, 87-96Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
VanGorp, C.L. +7 more
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