Results 101 to 110 of about 5,259 (265)

High-Value Components and Bioactives from Sea Cucumbers for Functional Foods—A Review

open access: yesMarine Drugs, 2011
Sea cucumbers, belonging to the class Holothuroidea, are marine invertebrates, habitually found in the benthic areas and deep seas across the world. They have high commercial value coupled with increasing global production and trade.
Nazamid Saari   +2 more
doaj   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

open access: yesBMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo   +9 more
wiley   +1 more source

Antibodies to Chondroitin Sulfates A, B, C: clinico-pathological correlates in neurological diseases

open access: yes, 2000
Anti-chondroitin sulfates (ChSs) antibodies have been reported in neuropathy and neurodegenerative diseases. Differences in specificities may account for their association with different diseases.
SANTORO M, LATOV N., BRIANI, CHIARA
core  

Chondroitin 4-Sulfate Disaccharide-Based Inhibitors of Cathepsin S

open access: yesPolysaccharides
Cathepsin S (Cat S) is a cysteine protease involved in several human diseases (i.e., autoimmune, inflammatory and cardiovascular disorders, cancer, and psoriasis) and is an important target in drug development.
Alexis David   +11 more
doaj   +1 more source

A Sweet Talk: The Molecular Systems of Perineuronal Nets in Controlling Neuronal Communication

open access: yesFrontiers in Integrative Neuroscience, 2017
Perineuronal nets (PNNs) are mesh-like structures, composed of a hierarchical assembly of extracellular matrix molecules in the central nervous system (CNS), ensheathing neurons and regulating plasticity.
Heleen M. van 't Spijker   +2 more
doaj   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara   +7 more
wiley   +1 more source

Evaluation of chondroitin sulfate bioactivity in hippocampal neurones and the astrocyte cell line U373: Influence of position of sulfate groups and charge density

open access: yes, 2005
Chondroitin sulfates are linear polysaccharides of alternating glucuronic acid and N-acetylgalactosamine, sulfated in varying positions. They form the extracellular framework providing the information for the structural establishment of tissues in ...
VOLPI, Nicola   +3 more
core   +1 more source

Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications

open access: yesExploration, EarlyView.
There are few reviews on hydrogel adhesives that comprehensively highlight the design principles, factors affecting adhesion, and applications for gastrointestinal (GI) perforation repair. This review outlines the mainstream design approaches of hydrogel adhesives via covalent and noncovalent molecular interactions, illustrating the underlying adhesive
Yudi Pang   +7 more
wiley   +1 more source

Commissural projection from the vestibular nucleus in rat embryos: role of chondroitin sulfates

open access: yes, 2007
To determine if chondroitin sulfates (CS) contribute restrictive guidance in commissural projections from the vestibular nucleus, we treated embryos (E12.5-14.5, Sprague-Dawley rats) with chondroitinase ABC or vehicle via the fourth ventricle for 24 hrs ...
Yuen, YL   +4 more
core  

Preparation and Biological Activity of N-Sulfated Chondroitin and Dermatan Sulfate Derivatives

open access: yes, 1996
Carbohydrate Research, 290, 87-96Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
VanGorp, C.L.   +7 more
core   +1 more source

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