Transforming growth factor (type beta) promotes the addition of chondroitin sulfate chains to the cell surface proteoglycan (syndecan) of mouse mammary epithelia. [PDF]
, 1989 Alan C. Rapraeger
openalex +1 more source
Extracellular Matrix Signaling Cues: Biological Functions, Diseases, and Therapeutic Targets
MedComm, Volume 6, Issue 8, August 2025.Targeting ECM dysregulation: therapeutic strategies for disease intervention. Dysregulated ECM composition and biomechanics contribute to disease pathogenesis in cancer and fibrotic disorders. Physical modulation: Nanomedicine‐based strategies tune ECM physical properties (e.g., density, stiffness) to enhance drug penetration and therapeutic efficacy ...
Tian Zhao +11 more
wiley +1 more source
Invariant chain is the core protein of the Ia-associated chondroitin sulfate proteoglycan. [PDF]
, 1985 Andrea J. Sant +3 more
openalex +1 more source
Osteoarthritis: Mechanisms and Therapeutic Advances
MedComm, Volume 6, Issue 8, August 2025.A schematic illustration of the pathogenesis and emerging therapeutic strategies for OA, including: risk factors and molecular mechanisms of OA, joint changes between healthy and OA conditions, and current emerging therapeutic approaches for OA. Abbreviations: IA: intra‐articular injection; EVs: extracellular vesicles. ABSTRACT Osteoarthritis (OA) is a
Wei Liu +3 more
wiley +1 more source
Membrane-associated chondroitin sulfate proteoglycans of human lung fibroblasts. [PDF]
, 1989 Gregory David +5 more
openalex +1 more source
Astrocyte in Neurological Disease: Pathogenesis and Therapy
MedComm, Volume 6, Issue 8, August 2025.This review provides comprehensive overview of astrocytes in neurological disorders. Astrocytes contribute to neurological disorders via A1/A2 polarization, inducing neuroinflammation, synaptic, and BBB dysfunction. Metabolic disturbances in glucose, lipid, and amino acid pathways leading to oxidative stress and mitochondrial damage.
Meihui Huang +4 more
wiley +1 more source
Exploiting enzyme specificities in digestions of chondroitin sulfates A and C: production of well-defined hexasaccharides. [PDF]
Glycobiology, 2012 Pomin VH +6 more
europepmc +1 more source
Histochemical differentiation between chondroitin 4-sulfate and chondroitin 6-sulfate.
, 1978 Yoichiro Sasai +3 more
openalex +2 more sources