The draft genome of the tropical sea cucumber Stichopus monotuberculatus (Echinodermata, Stichopodidae) reveals critical genes in fucosylated chondroitin sulfates biosynthetic pathway. [PDF]
Zhong S+10 more
europepmc +1 more source
The identification of proteoglycans and glycosaminoglycans in archaeological human bones and teeth [PDF]
Bone tissue is mineralized dense connective tissue consisting mainly of a mineral component (hydroxyapatite) and an organic matrix comprised of collagens, non-collagenous proteins and proteoglycans (PGs).
A Hildebrand+70 more
core +2 more sources
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi+2 more
wiley +1 more source
Chondroitin Sulfates Control Invasiveness of the Basal-Like Breast Cancer Cell Line MDA-MB-231 Through ROR1. [PDF]
Nadanaka S, Tamura JI, Kitagawa H.
europepmc +1 more source
Microfluidic Synthesis of Collagen‐Based Microgels for Tissue Engineering Applications
We present a droplet microfluidic approach for preparing porous and irregularly shaped microgels of fibrillar collagen and collagen‐glycosaminoglycan (GAG) copolymer in a continuous oil phase at rates of up to 5500 s−1. ABSTRACT To expand the use of collagen‐based biomaterials beyond their current applications in three‐dimensional (3D) cell culture ...
Ehsan Samiei+2 more
wiley +1 more source
Microbiological-Chemical Sourced Chondroitin Sulfates Protect Neuroblastoma SH-SY5Y Cells against Oxidative Stress and Are Suitable for Hydrogel-Based Controlled Release. [PDF]
Bedini E+7 more
europepmc +1 more source
Bioactive and bactericidal biocomposites based on PBAT/PLA with hydroxyapatite and tannin derivative
Preparation of biocomposites based on PBAT/PLA with hydroxyapatite and tannin derivative. Abstract The aim of this study was to develop innovative bioactive and bactericidal composites by enhancing the biodegradable Ecovio® blend, composed of poly(butylene adipate‐co‐terephthalate) (PBAT) and poly(lactic acid) (PLA), with hydroxyapatite (HA) and an ...
Ewerton de Oliveira Teotônio Bezerra+6 more
wiley +1 more source
Glycans and glycosaminoglycans in neurobiology: key regulators of neuronal cell function and fate [PDF]
The aim of the present study was to examine the roles of l-fucose and the glycosaminoglycans (GAGs) keratan sulfate (KS) and chondroitin sulfate/dermatan sulfate (CS/DS) with selected functional molecules in neural tissues.
Hayes, Anthony J., Melrose, James
core +2 more sources
Diverse reactivity of maleimides in polymer science and beyond
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick+2 more
wiley +1 more source
Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri+11 more
wiley +1 more source