Results 141 to 150 of about 12,385 (266)
Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie +21 more
wiley +1 more source
Chordality Properties and Hyperbolicity on Graphs
Let $G$ be a graph with the usual shortest-path metric. A graph is $\delta$-hyperbolic if for every geodesic triangle $T$, any side of $T$ is contained in a $\delta$-neighborhood of the union of the other two sides. A graph is chordal if every induced cycle has at most three edges.
openaire +3 more sources
• Excitatory neurons and astrocytes show marked alterations in the single‐cell spatial transcriptomic atlas of epileptogenic cortex from patients with focal cortical dysplasia type I (FCDI). • The CBLN2high excitatory neuron subtype may be associated with neuronal hyperexcitability and cortical development in FCDI.
Yaqian Zhang +9 more
wiley +1 more source
Abstract Background Midline establishment is a fundamental process during early embryogenesis for Bilaterians. Midline morphogenesis in non‐amniotes can occur without mitosis, through Planar Cell Polarity (PCP) signaling. By contrast, amniotes utilize both cellular processes for developing the early midline landmark, the primitive streak (PS).
Zhiling Zhao, Rieko Asai, Takashi Mikawa
wiley +1 more source
Chordal bipartite, strongly chordal, and strongly chordal bipartite graphs
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Urinary Extracellular Vesicles for High‐Precision Bladder Cancer Subtyping and Prognosis
ABSTRACT Bladder cancer (BCa) exhibits molecular heterogeneity that complicates early diagnosis and prognosis, and drives confounding clinical outcomes. Non‐muscle invasive and muscle‐invasive subtypes, especially for intermediate to high grade, carry a 25%–50% progression‐free survival rate, underscoring the need for high‐precision prognostic strategy.
Zachary F. Greenberg +5 more
wiley +1 more source
On the uniqueness of collections of pennies and marbles
In this note we study the uniqueness problem for collections of pennies and marbles. More generally, consider a collection of unit d-spheres that may touch but not overlap.
Sean Dewar +4 more
doaj +1 more source
Abstract Non‐vesicular lipid transport contributes to the regulation of membrane composition and organelle function at membrane contact sites. OSBP‐related proteins (ORPs) are central to this process, yet their interaction networks remain incompletely defined. Here, we systematically screened potential interactions between ORPs and phosphoinositide 3‐,
Filippo Dall'Armellina +2 more
wiley +1 more source
ABSTRACT Marine ecosystems are increasingly threatened by overfishing, pollution, coastal development and climate change, underscoring the need for long‐term, representative information on key fish populations and habitats to inform management and policy.
Angus John van Wyk +26 more
wiley +1 more source
Entrywise transforms preserving matrix positivity and nonpositivity
Abstract We characterize real and complex functions which, when applied entrywise to square matrices, yield a positive definite matrix if and only if the original matrix is positive definite. We refer to these transformations as sign preservers. Compared to the classical work on entrywise preservers by Schoenberg and others, we completely resolve this ...
Dominique Guillot +3 more
wiley +1 more source

