Results 151 to 160 of about 2,481 (263)

APOE*4 risk‐modifying genes and drug targets in Alzheimer's disease through cell‐type‐specific genomic analyses

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Genetics studies can identify drug targets that counteract the effects of the apolipoprotein E ε4 allele (APOE*4) on Alzheimer's disease (AD) but have remained limited in power and crucially did not assess genetic findings with regard to APOE*4's cell‐type‐specific impact on pathobiology.
Youjie Zeng, Noah Cook, Chenyu Yang, Sathesh K. Sivasankaran, Masashi Fujita, Zachary A. Gardell, Yann Le Guen, Daichi Shigemizu, Kouichi Ozaki, Takashi Morizono, Norikazu Hara, Akinori Miyashita, Takeshi Ikeuchi, Cyril Pottier, Carlos Cruchaga, Valerio Napolioni, M. Ryan Corces, Vilas Menon, Michael D. Greicius, Michael E. Belloy   +19 more
wiley   +1 more source

Integrated Orbitrap‐HRMS and Chemometric Profiling Reveals Metabolite Diversity and Antioxidant Signatures in Cerrado Eugenia Fruits

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Fruits from the Brazilian Cerrado, such as pitanga (Eugenia uniflora), jambolao (E. jambolana) and murta (E. punicifolia), are recognized for their nutritional and therapeutic potential, largely due to their phenolic‐rich profiles. However, systematic studies integrating high‐resolution mass spectrometry (HRMS) with chemometric tools to ...
Alexandre W. V. Nascimento, Naará S. Balbino, Salva Asghar, Erica A. Batista, Eric de Souza Gil, Abeer M. Alawi Al‐Sakkaf, Boniek G. Vaz, Teresinha J. A. S. Andrade, Nerilson Marques Lima   +8 more
wiley   +1 more source

On groups with chordal power graph, including a classification in the case of finite simple groups [PDF]

We prove various properties on the structure of groups whose power graph is chordal. Nilpotent groups with this property have been classified by (Electron J Combin 28(3):14, 2021).
Kaja, Eda, Brachter, Jendrik
core   +1 more source

Bone Marrow Failure Model Mimics Aplastic Anemia Patients: Single‐Cell Landscape of Immune Response Reveals Novel Mechanisms of Immune Imbalance in AA

Cancer Medicine, Volume 15, Issue 6, June 2026.
Single‐cell RNA‐seq is used in a mouse model of immune‐mediated bone marrow failure. Approach to platelets and mitochondrial data. Analysis of various immune cell landscapes, interactions and driving factors in BMF, involving platelets, CD4+ T Cells, CD8+ T Cells, macrophages, and mitochondrial energy metabolism pathways.
Shuai Tan, Fang Fang, Jing Sun, Yumeng Li, Yaochi Chen, Wanling Sun   +5 more
wiley   +1 more source

First‐line envafolimab plus recombinant human‐endostatin in advanced non–small cell lung cancer with PD‐L1 tumor proportion score ≥1% (Endouble): A multicenter, prospective, single‐arm, phase 2 trial

Cancer, Volume 132, Issue 11, 1 June 2026.
Envafolimab combined with recombinant human endostatin demonstrates favorable efficacy and tolerable toxicity in non–small cell lung cancer patients. MMP1 and TNFRSF6B may be predictive biomarkers for treatment response. Abstract Background This trial evaluates the efficacy and safety of combining envafolimab and recombinant human endostatin (Rh ...
Changhong Dong, Liang Liu, Yun Qiao, Mei Wang, Daan Song, Lihua Zhou, Yajun Ji, Yan Li, Fendou Ding, Hao Wang, Min Zhuang, Lei Wang, Zhenghong Liu, Haitao Fei, Xiangjun Guo, Baoxiang Bian, Chunluan Yuan, Guanghui Xu, Lijian Fang, Yan Li, Ziyan Song, Kaiyuan Hui, Xiaodong Jiang   +22 more
wiley   +1 more source

Single‐cell profiling reveals peripheral blood immune landscape remodelling in breast cancer lymph node metastasis

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
scRNA‐seq reveals pro‐metastatic neutrophil and exhausted T/NK subsets in BC patients with LN metastasis. Interferon‐stimulated neutrophils secrete LGALS9, drives T/NK cell exhaustion via HAVCR2. Neutralising LGALS9 restores T‐cell anti‐tumour activity, suggesting a novel therapeutic target.
Bo Chen, Kang Ma, Yunjie Wang, Liulu Zhang, Xinyue Feng, Cheng Long, Xuejing Tan, Kun Wang   +7 more
wiley   +1 more source

Graph classes related to chordal graphs and chordal bipartite graphs

Electronic Notes in Discrete Mathematics, 2006
Nguyen Ngoc Tuy, Jörg Bornemann, Van Bang Le   +2 more
openaire   +1 more source

Application of Music Data Visualization Technology in Music Appreciation Teaching

Engineering Reports, Volume 8, Issue 6, June 2026.
The simulation environment is used to simulate real‐world music appreciation scenarios. DL is employed to preprocess music data, extract features, and identify rhythm information, which is then associated with visual design parameters to construct a parametric model.
Xiaowei Chen
wiley   +1 more source

Treewidth of chordal bipartite graphs

, 1992
Chordal bipartite graph are exactly those bipartite graph in which every cycle of length at least six has a chord. The treewidth of a graph G is the smallest maximum cliquesize among all chordal supergraphs of G decreased by one.

core  

Comparing trees characteristic to chordal and dually chordal graphs [PDF]

Chordal and dually chordal graphs possess characteristic tree representations, namely, clique trees and compatible trees, respectively. The following problem is studied: given a chordal graph G, it has to be determined if the clique trees of G are ...
De Caria, Pablo Jesús, Gutiérrez, Marisa   +1 more
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