Results 151 to 160 of about 919,306 (297)
The Hippo pathway transcription factor TEAD3 represents an independent prognostic biomarker of tumor recurrence and a potential therapeutic vulnerability through its regulation of cholesterol metabolism in glioma. Abstract Glioblastomas represent the most common and lethal primary brain tumors in the world.
Konstantin Masliantsev +10 more
wiley +1 more source
Modeling Multivariate Spatial Dependencies Using Graphical Models. [PDF]
Dey D, Datta A, Banerjee S.
europepmc +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Labeling algorithms for domination problems in sun-free chordal graphs
Gerard J. Chang
openalex +1 more source
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou +16 more
wiley +1 more source
scRNA sequencing reveals distinct tumor ecosystem features in CAYA‐PTC, marked by enriched CD4T_Tfh, CD8T_Tex cells, and rapid malignant thyrocyte differentiation (absent of mild‐state BRAF‐like population) toward invasive states. Prominent emCAF_LAMP5 populations interact with endothelial cells and thyrocytes facilitate angiogenesis and metastasis ...
Kai Guo +15 more
wiley +1 more source
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan +4 more
wiley +1 more source
A simple algorithm to generate the minimal separators and the maximal cliques of a chordal graph
Anne Berry, Romain Pogorelcnik
semanticscholar +1 more source
Biomolecular Interaction Prediction: The Era of AI
This review offers a thorough examination of recent progress in deep learning for predicting biomolecular interactions, including those involving proteins, nucleic acids, and small molecules. It covers data processing strategies, representative model architectures, and evaluation metrics, while highlighting current methodological limitations.
Haoping Wang, Xiangjie Meng, Yang Zhang
wiley +1 more source
Classes of bipartite graphs related to chordal graphs
Andreas Brandstädt
openalex +1 more source

