Results 151 to 160 of about 946,691 (269)

DNTTIP1 drives leukaemogenesis through MiDAC‐mediated epigenetic silencing of BMF

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
DNTTIP1 cooperates with SP1 to recruit HDAC1/2, leading to BMF silencing and reduced competitive binding of BMF to BCL2.This suppresses autophagy and apoptosis, promoting leukaemic cell survival. Targeting the DNTTIP1‐HDAC1/2‐BMF axis reactivates BMF and induces anti‐leukaemic effects.
Ruolin Xiu, Yuzhu Ma, Yueying Gao, Yao Chen, Xinyu Li, Yue Wu, Meiling Sun, Qizhao Li, Yanhong Zhao, Shuqian Xu, Shengjin Fan, Yongsheng Li, Huitao Fan   +12 more
wiley   +1 more source

Modeling Multivariate Spatial Dependencies Using Graphical Models. [PDF]

N Engl J Stat Data Sci, 2023
Dey D, Datta A, Banerjee S.
europepmc   +1 more source

Integer Laplacian Eigenvalues of Chordal Graphs [PDF]

Linear Algebra and its Applications, 2019
N. Abreu, C. Justel, L. Markenzon
semanticscholar   +1 more source

Comprehensive tumour‐immune profiling reveals TREM2+ tumour‐associated macrophages facilitating lymph node metastasis in head and neck squamous cell carcinoma

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
(1) TREM2+ TAMs promote CD8+ T cell exhaustion by upregulating BHLHE40 through the SPP1–CD44 axis, contributing to a suppressive tumour immune microenvironment in HNSCC. (2) CD8+ Tex induced by TREM2+ TAMs facilitates immune escape and promotes tumour cell metastasis via the lymphangion.
Zhuokai Wu, Chixing Cheng, Zhaoxin Li, Minyi Ren, Hongxi Cao, Weijie Huang, Jun Wang, Lixian Wu, Tingyi Lee, Sien Zhang, Hanhao Zheng, Yixi Wang   +11 more
wiley   +1 more source

Evaluating Antibiotic Resistance in Urban Rivers and Coral Reefs of Belize: Evidence for Hotspots and a Potential Screening Tool

GeoHealth, Volume 10, Issue 2, February 2026.
Abstract Antibiotic resistance is a significant threat to global public health and can disproportionately affect low‐ and middle‐ income countries (LMICs). There is a lack of studies focusing on antibiotic resistance in coral reef regions and environmental reservoirs in Central America.
Ileana A. Galdamez, Karina Jimenez, Marisol Cira, Katie Osborn, Mariam Ayad, Christine M. Lee, Kai Patel, Bryan A. Galdamez, Ashlyn Sloan, Alexis Shenkiryk, Taylor Cason, Nicole Auil Gomez, Myles Phillips, Samir Rosado, Andria Rosado, Deepak R. Mishra, Emil A. Cherrington, Robert Griffin, Jennifer A. Jay   +18 more
wiley   +1 more source

Algorithm‐Based Common Microcirculatory Framework for Monitoring and Visualizing the Integrated Pancreatic Microcirculation in Type 2 Diabetes Mellitus Mice

Journal of Diabetes, Volume 18, Issue 2, February 2026.
Integrated monitoring of the pancreatic microcirculation utilizes a multimodal probe to simultaneously acquire microhemodynamic and oxygenation data through combined laser Doppler flowmetry and diffuse reflectance spectroscopy (DRS). Raw signals undergo algorithmic processing to extract speed‐resolved blood perfusion (BP) parameters, categorized into ...
Yuan Li, Yingyu Wang, Bing Wang, Weiqi Liu, Mengting Xu, Xiaoyan Zhang, Xueting Liu, Hao Ling, Xu Zhang, Mingming Liu, Ruijuan Xiu   +10 more
wiley   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

Detecting and Modeling Emotional Landscapes Through Deep Learning, GPT‐4.1, and 3D Spatial Interpolation

Transactions in GIS, Volume 30, Issue 1, February 2026.
ABSTRACT This research provides new directions in conceptualizing emotional geographies at the landscape level using a combination of textual deep learning (DL) and GPT‐based spatial emotion detection and interpolation using 3D empirical Bayesian kriging.
Christopher J. Anderson
wiley   +1 more source

Parameterized Complexity and Inapproximability of Dominating Set Problem in Chordal and Near Chordal Graphs. [PDF]

J Comb Optim, 2010
Liu C, Song Y.
europepmc   +1 more source

Nearly Hamilton cycles in sublinear expanders and applications

Journal of the London Mathematical Society, Volume 113, Issue 2, February 2026.
Abstract We develop novel methods for constructing nearly Hamilton cycles in sublinear expanders with good regularity properties, as well as new techniques for finding such expanders in general graphs. These methods are of independent interest due to their potential for various applications to embedding problems in sparse graphs.
Shoham Letzter, Abhishek Methuku, Benny Sudakov   +2 more
wiley   +1 more source