Results 61 to 70 of about 235 (177)

On the multipacking number of grid graphs [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2019
In 2001, Erwin introduced broadcast domination in graphs. It is a variant of classical domination where selected vertices may have different domination powers. The minimum cost of a dominating broadcast in a graph $G$ is denoted $\gamma_b(G)$.
Laurent Beaudou, Richard C. Brewster
doaj   +1 more source

On the pathwidth of chordal graphs

open access: yesDiscrete Applied Mathematics, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

open access: yesAdvanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao   +6 more
wiley   +1 more source

Efficient (j, k)-Dominating Functions

open access: yesDiscussiones Mathematicae Graph Theory, 2023
For positive integers j and k, an efficient (j, k)-dominating function of a graph G = (V, E) is a function f : V → {0, 1, 2, . . ., j} such that the sum of function values in the closed neighbourhood of every vertex equals k. The relationship between the
Klostermeyer William F.   +3 more
doaj   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

open access: yesAdvanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng   +19 more
wiley   +1 more source

The Topological Connectivity of the Independence Complex of Circular-Arc Graphs

open access: yesUniversal Journal of Mathematics and Applications, 2019
Let us denoted the topological connectivity of a simplicial complex $C$ plus 2 by $\eta(C)$. Let $\psi$ be a function from class of graphs to the set of positive integers together with $\infty$. Suppose $\psi$ satisfies the following properties: \newline
Yousef Abd Algani
doaj   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang   +12 more
wiley   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

open access: yesAdvanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao   +6 more
wiley   +1 more source

On a Class of Graphs with Large Total Domination Number [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2018
Let $\gamma(G)$ and $\gamma_t(G)$ denote the domination number and the total domination number, respectively, of a graph $G$ with no isolated vertices. It is well-known that $\gamma_t(G) \leq 2\gamma(G)$.
Selim Bahadır, Didem Gözüpek
doaj   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

open access: yesAdvanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu   +7 more
wiley   +1 more source

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