Results 71 to 80 of about 11,717 (208)

Nitric Oxide regulates mouth development in amphioxus

Scientific Reports, 2017
The development of the mouth in animals has fascinated researchers for decades, and a recent study proposed the modern view of recurrent evolution of protostomy and deuterostomy. Here we expanded our knowledge about conserved traits of mouth formation in
Giovanni Annona, Filomena Caccavale, Juan Pascual-Anaya, Shigeru Kuratani, Pasquale De Luca, Anna Palumbo, Salvatore D’Aniello   +6 more
doaj   +1 more source

Defining the role of αC helix interactions in the activation of the integrin αI domain

The FEBS Journal, EarlyView.
The α2I domain of the α2β1 integrin contains a distinctive αC helix and a conserved Arg288‐Glu318 ion pair that stabilizes the closed state of the domain. Disruption of this ion pair in the activated α2I variant unwinds the αC helix, which allows interaction with additional collagen‐binding sites increasing collagen binding.
Liisa Pösö, Tomi T. Airenne, Jarmo Käpylä, Hongmin Tu, Eva Bligt‐Lindén, Vimal Parkash, Jyrki Heino, Tiina A. Salminen   +7 more
wiley   +1 more source

Mast Cells in Host Defense Against Cutaneous Staphylococcus aureus Infection

Immunology &Cell Biology, EarlyView.
Impact of S. aureus epicutaneous sensitization models on mast cell function in vivo. D. farinae and Staphylococcal enterotoxin B (SEB) activate Trpv1+ Tac1+ nociceptors to trigger the release of substance P (SP), which promotes mast cell degranulation through Mrgprb2. S.
Hannah Dychtenberg, Carly Kadonoff, Bailey Lehnert, Priyanka Pundir   +3 more
wiley   +1 more source

Ancestral role of Pax6 in chordate brain regionalization

Frontiers in Cell and Developmental Biology
The Pax6 gene is essential for eye and brain development across various animal species. Here, we investigate the function of Pax6 in the development of the anterior central nervous system (CNS) of the invertebrate chordate amphioxus using CRISPR/Cas9 ...
Zbynek Kozmik, Iryna Kozmikova
doaj   +1 more source

Molecular evolution of a chordate specific family of G protein-coupled receptors

BMC Evolutionary Biology, 2011
Background Chordate evolution is a history of innovations that is marked by physical and behavioral specializations, which led to the development of a variety of forms from a single ancestral group.
Leese Florian, Hatt Hanns, Pelz Thomas, Mayer Christoph, Kurtenbach Stefan, Neuhaus Eva M   +5 more
doaj   +1 more source

Surveying Biodiverse Coral Reef Ecosystems Across the Tree of Life With Environmental DNA

Molecular Ecology Resources, Volume 26, Issue 7, October 2026.
ABSTRACT A central challenge in evaluating biodiversity using environmental DNA (eDNA) metabarcoding is that each primer set has biases resulting in selective amplification of taxonomic diversity. Here we test 11 primer pairs to assess Central Pacific coral reef diversity in the five kingdoms of marine eukaryotes: Chromista, Fungi, Metazoa, Plantae and
Van Wishingrad, Brian W. Bowen, Robert J. Toonen   +2 more
wiley   +1 more source

From the sea to DNA barcode: Optimized preservation method for gelatinous zooplankton integrative taxonomy

Limnology and Oceanography: Methods, Volume 24, Issue 9, September 2026.
Abstract Assigning taxonomic identity and thus assessing taxonomic diversity in gelatinous zooplankton is challenging due to their fragility and difficult preservation. Formalin fixation compromises DNA integrity, while flash‐freezing, ethanol, and acetone preservation affect morphological features. In this study, we developed a methodological protocol
Claudia Traboni, Rade Garić, Rita Marino, Paolo Sordino, Priscilla Licandro   +4 more
wiley   +1 more source

Transforming Life Science Through Chromosome‐Level Genome Assemblies

Genes to Cells, Volume 31, Issue 5, September 2026.
Chromosome‐level genome assemblies provide a framework for “glocal biology” in species of interest, linking local molecular features to chromosome architecture and evolutionary context. When integrated with pangenome analysis, comparative multi‐omics, genome language models, and experimental approaches, these assemblies enable hypothesis generation and
Tetsuo Kon, Kosuke Kataoka, Yi‐Jyun Luo, Johannes Nicolaus Wibisana, Kouhei Toga, Narumi Uno, Yuki Monden, Mayuko Hamada   +7 more
wiley   +1 more source

Evolutionary scenario for somitogenesis in chordates.

, 2015
Evolutionary relationships among the three chordate clades are presented, as well as a schematic view of the morphology of embryos of the putative ancestor of chordates, cephalochordates, tunicates and vertebrates (all dorsal views except tunicates for ...
Angel R. de Lera (1811737), Hector Escriva (17387), Lucie Subirana (796193), Stéphanie Bertrand (17383), Daniel Aldea (796192), Silvan Oulion (165649), Ildiko Somorjai (796194)   +6 more
core   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, Volume 13, Issue 48, 28 August 2026.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source