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Mutational analysis of primary and advanced chordoma tissue using next-generation sequencing. [PDF]
CancerChan J +10 more
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Proton beam radiation therapy vs. photon radiation therapy and the overall survival of adult and pediatric patients diagnosed with sarcoma. [PDF]
Front OncolAmin SA, Mateen ZA, Amin P, Lin C.
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Current Opinion in Oncology, 2007
To review developments in chordoma treatment.Recent series with prolonged follow-up show that adequate margins are necessary for surgery to be curative. Safe margins are often difficult to obtain due to the anatomical sites of chordoma: sacrum, skull base and spine.
Paolo G, Casali +4 more
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To review developments in chordoma treatment.Recent series with prolonged follow-up show that adequate margins are necessary for surgery to be curative. Safe margins are often difficult to obtain due to the anatomical sites of chordoma: sacrum, skull base and spine.
Paolo G, Casali +4 more
openaire +2 more sources
Current Treatment Options in Neurology, 2002
Optimal therapy of chordoma is a combined approach of surgical resection followed by proton beam irradiation for residual disease. The goals of surgery are to establish a definitive diagnosis, obtain total or maximal resection, and "shape" any residual disease so that it is favorable for radiation. Given the difficult locations and large sizes of these
Saad, Khairi, Matthew G., Ewend
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Optimal therapy of chordoma is a combined approach of surgical resection followed by proton beam irradiation for residual disease. The goals of surgery are to establish a definitive diagnosis, obtain total or maximal resection, and "shape" any residual disease so that it is favorable for radiation. Given the difficult locations and large sizes of these
Saad, Khairi, Matthew G., Ewend
openaire +2 more sources
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2014
Chordomas are malignant tumors of the axial skeleton, characterized by their locally invasive and slow but aggressive growth. These neoplasms are presumed to be derived from notochordal remnants with a molecular alteration preceding their malignant transformation.
Yakkioui, Youssef +4 more
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Chordomas are malignant tumors of the axial skeleton, characterized by their locally invasive and slow but aggressive growth. These neoplasms are presumed to be derived from notochordal remnants with a molecular alteration preceding their malignant transformation.
Yakkioui, Youssef +4 more
openaire +3 more sources
Journal of the American Academy of Dermatology, 2005
Chordomas are rare malignant primary bone tumors, which most often occur in the sacral area. These tumors uncommonly affect the skin, and may not be recognized by dermatologists. We present a case of an adult woman with cutaneous metastasis of a primary sacral chordoma.
Adam I, Rubin +2 more
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Chordomas are rare malignant primary bone tumors, which most often occur in the sacral area. These tumors uncommonly affect the skin, and may not be recognized by dermatologists. We present a case of an adult woman with cutaneous metastasis of a primary sacral chordoma.
Adam I, Rubin +2 more
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Clinical Orthopaedics and Related Research, 1986
Chordomas constitute between 1% and 4% of primary malignant bone tumors. Approximately 50% originate in the sacrum, 35% at the base of the skull, and 15% in the true vertebrae. The majority of tumors are encountered from the fifth through seventh decades, with a male preponderance.
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Chordomas constitute between 1% and 4% of primary malignant bone tumors. Approximately 50% originate in the sacrum, 35% at the base of the skull, and 15% in the true vertebrae. The majority of tumors are encountered from the fifth through seventh decades, with a male preponderance.
openaire +2 more sources