Results 41 to 50 of about 22,213 (195)

Case Report: 18F-FDG PET/CT and Laparoscopic Nephron Sparing Surgery in the Management of Bleeding From Renal Metastases of Choriocarcinoma

Frontiers in Oncology, 2022
Choriocarcinoma is a cancer that usually occurs in the uterus during pregnancy. Although choriocarcinoma with renal metastasis and spontaneous renal hemorrhage is very rare, it can occur. We describe a rare case of metastatic choriocarcinoma, wherein the
Yuancheng Du, Xueping Zhang, Shengyang Sun, Meihong Sun, Dongyu Yang, Xinyuan Yu, Kehao Li, Jie Ma, Yongxiang Li, Jinming Ge, Changqing Liu, Liang Qiao   +11 more
doaj   +1 more source

Delayed diagnosis of intraplacental choriocarcinoma in a term healthy neonate—A case report and literature review

Clinical Case Reports, 2022
Gestational choriocarcinoma is rare. The intraplacental formation of choriocarcinoma is much rarer. We present a diagnosis of choriocarcinoma, 4 months postpartum, in a 28‐year‐old, presenting with vaginal bleeding.
Mahdokht Azizi, Mojgan Akbarzade‐Jahromi, Parvin Ghaffari, Mazaher Ramezani   +3 more
doaj   +1 more source

Targeted Delivery Prodigiosin to Choriocarcinoma by Peptide-Guided Dendrigraft Poly-l-lysines Nanoparticles

International Journal of Molecular Sciences, 2019
The available and effective therapeutic means to treat choriocarcinoma is seriously lacking, mainly due to the toxic effects caused by chemotherapy and radiotherapy.
Kai Zhao, Dan Li, Guogang Cheng, Baozhen Zhang, Jinyu Han, Jie Chen, Baobei Wang, Mengxia Li, Tianxia Xiao, Jian V. Zhang, Dong-po Zhou, Zheng Jin, Xiujun Fan   +12 more
semanticscholar   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Male choriocarcinoma presenting with intracerebral hemorrhage: a case report and literature review

Frontiers in Oncology
Male choriocarcinoma is an extremely rare malignant tumor. It has the characteristics of hidden onset, easy invasion and metastasis. Clinically, when choriocarcinoma is found in a patient, most of the tumor cells have metastasized to distant organs. This
Jie Chen, Yu He, Junwen Ao, Zhengshi Wang, Kuan Yang, Miao Chen, Xing Zhao   +6 more
doaj   +1 more source

Cutaneous Manifestation of Metastatic Infantile Choriocarcinoma

Case Reports in Pediatrics, 2014
Infantile choriocarcinoma is a highly malignant rare germ cell tumor that arises from the placenta. Simultaneous intraplacental choriocarcinoma involving both mother and infant is extremely rare.
Timothy Brooks, Laura Nolting
doaj   +1 more source

Targeting MGAT4A‐Mediated N‐Glycosylation as a Therapeutic Strategy to Inhibit Glioblastoma Stem Cell Invasion

Exploration, EarlyView.
ABSTRACT Glioblastoma (GBM) is the most aggressive type of primary brain tumor, and its invasive properties contribute significantly to incomplete surgical resection and tumor recurrence. Despite extensive clinical efforts to mitigate GBM invasion, targeted therapies against GBM stem cells (GSCs), which drive invasion, remain incompletely understood ...
Rui Niu, Meichen Liu, Qingshan Yang, Jinlong Yin   +3 more
wiley   +1 more source

Using short tandem repeat analysis for choriocarcinoma diagnosis: a case series

Diagnostic Pathology, 2019
BackgroundChoriocarcinoma is a highly aggressive, malignant trophoblastic neoplasm that can be gestational or non-gestational in origin. Accurate discrimination between these two subtypes, the causative pregnancy type, and the pregnancy-to-treatment ...
Xiaofei Zhang, K. Yan, Jianhua Chen, Xing Xie   +3 more
semanticscholar   +1 more source

AMHR2 mutation in persistent Müllerian duct syndrome: A case of transverse testicular ectopia

UroPrecision, EarlyView.
Abstract Backgroud Persistent Müllerian duct syndrome (PMDS) is a rare condition characterized by the persistence of Müllerian duct structures in genotypic and phenotypic males. Case Presentation We present the case of a 4‐month‐old male with PMDS who presented with transverse testicular ectopia. The patient underwent diagnostic laparoscopic orchiopexy
Hangcheng Fu, Weijing Huang, Jeffrey T. White   +2 more
wiley   +1 more source

Dual-responsive, Methotrexate-loaded, Ascorbic acid-derived Micelles Exert Anti-tumor and Anti-metastatic Effects by Inhibiting NF-κB Signaling in an Orthotopic Mouse Model of Human Choriocarcinoma

Theranostics, 2019
Gestational trophoblastic neoplasia (GTN), the most aggressive form of which is choriocarcinoma, can result from over-proliferation of trophoblasts.
Lili Wei, Chenyuan Wang, Xianjue Chen, Bing-Hu Yang, Kun Shi, Leah Benington, L. Lim, Sanjun Shi, Jingxin Mo   +8 more
semanticscholar   +1 more source