Results 61 to 70 of about 12,426 (192)

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell   +3 more
wiley   +1 more source

MCT1‐mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell‐derived barrier model

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Propionate in the fetal circulation is thought to originate from fermentation of dietary fibre by the maternal gut microbiota. However, the mechanism of transplacental transport has remained unclear. Here, we measured propionate permeability using a placental barrier model generated by differentiating human placental trophoblast ...
Toshiaki Tsuchitani   +8 more
wiley   +1 more source

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass   +2 more
wiley   +1 more source

A Biologically Dominant Trophoblastic Component Guiding Neoadjuvant EMA/CO in Endometrial Carcinoma: A Clinical Case Report

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Endometrial carcinoma with choriocarcinomatous components (ECCC) is a rare and aggressive malignancy for which optimal management remains undefined. We report a case illustrating how preoperative identification of a biologically dominant trophoblastic component can guide treatment sequencing and achieve durable remission.
Shinsuke Shirakawa   +15 more
wiley   +1 more source

Choriocarcinoma of the breast; A case report and review of literatures

open access: yesJournal of Research in Medical Sciences, 2011
Choriocarcinoma is an extremely rare pathology among breast malignancies. It is introduced by two distinct terms in the literatures: breast cancer with choriocarcinomatous features and metastatic choriocarcinoma to the breast.
Simin Hemati   +3 more
doaj  

Prevalence, Associated Factors, and Evaluation of Clinical and Biochemical Indices of Gestational Trophoblastic Tumors in Patients Referring to Imam Reza Hospital, Kermanshah: A Five‐Year Analytical Study (2017–2022)

open access: yesHealth Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Gestational trophoblastic neoplasia (GTN) encompasses a spectrum of pregnancy‐related disorders and poses significant clinical challenges. Understanding its prevalence, clinical characteristics, and associated risk factors is essential for timely diagnosis and management.
Nasrin Mansouri   +4 more
wiley   +1 more source

Spontaneous acute subdural hematoma as an initial presentation of choriocarcinoma: A case report

open access: yesJournal of Medical Case Reports, 2008
Introduction Diverse sequelae of central nervous system metastasis of choriocarcinoma have been reported, including infarction, intra or extra axial hemorrhages, aneurysm formation and carotid-cavernous fistula. Here we report a case of subdural hematoma
Rocque Brandon G, Başkaya Mustafa K
doaj   +1 more source

Contrast‐enhanced ultrasonography vs MRI for indeterminate testicular lesions: a systematic review and meta‐analysis

open access: yesBJU International, Volume 138, Issue 1, Page 57-67, July 2026.
Objective To conduct a systematic review and meta‐analysis to indirectly compare the diagnostic performance of contrast‐enhanced ultrasonography (CEUS) and magnetic resonance imaging (MRI) in the evaluation of indeterminate testicular lesions and to explore their potential roles in guiding clinical decision‐making.
Muhammed Arif Ibis   +14 more
wiley   +1 more source

A pure nongestational choriocarcinoma of the ovary

open access: yesJournal of Research in Medical Sciences, 2007
<p style="text-align: justify" class="MsoNormal">Choriocarcinoma arises in the ovary from gestational or nongestational origin. Nongestational choriocarcinoma of the ovary is extremely rare and the pure type is less frequent than the mixed type ...
Mohammad Ali Roghaei   +2 more
doaj  

Diagnostic yield of OCT3/4 reflex testing in testicular biopsy

open access: yesHistopathology, Volume 89, Issue 1, Page 136-143, July 2026.
GCNIS detection frequency was 48/3353 (1.4%) testicular biopsies from 42/1870 (2.2%) men who underwent testicular biopsy with or without testicular sperm extraction (TESE). OCT3/4 was particularly helpful for detecting interstitial seminoma, GCNIS coexisting with mature spermatogenesis, and focal GCNIS.
Roselyne Choiniere   +2 more
wiley   +1 more source

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