Results 41 to 50 of about 16,830 (216)

Choriocarcinoma [PDF]

, 2019
Koriokarcinom je jedan od histoloških tipova entiteta zvanog gestacijske trofoblastične neoplazije (GTN) koji nastaju abnormalnom proliferacijom tkiva trofoblasta, kojima može prethoditi bilo hidatiformna mola ili nemolarna trudnoća.
Ljoka, Ivan
core   +1 more source

Drug library screening identifies histone deacetylase inhibition as a novel therapeutic strategy for choriocarcinoma

Cancer Medicine, 2023
Background Choriocarcinoma is a rare and aggressive gynecological malignancy. The standard treatment is systemic chemotherapy as choriocarcinoma exhibits high chemosensitivity.
Eri Watanabe, Akira Yokoi, Kosuke Yoshida, Mai Sugiyama, Masami Kitagawa, Kimihiro Nishino, Eiko Yamamoto, Kaoru Niimi, Yusuke Yamamoto, Hiroaki Kajiyama   +9 more
doaj   +1 more source

Longitudinal AMH trajectories, ovarian reserve recovery, and fertility outcomes after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia: A real‐world cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To characterize anti‐Müllerian hormone (AMH) recovery after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia (GTN) and evaluate the impact of regimen and hysterectomy. Methods This was a retrospective cohort of 68 high‐risk GTN patients treated with EMA/CO (etoposide, methotrexate, actinomycin D ...
Wei Xue, Tianyi Chen, Yuxiao Wu, Tong Ren, Jun Zhao, Fengzhi Feng, Xirun Wan, Yang Xiang, Junjun Yang   +8 more
wiley   +1 more source

\ud Case Report: Unsuspected Uterine Choriocarcinoma with Lung Metastasis\ud [PDF]

, 2010
Choriocarcinoma is a rare form of cancer which commonly occurs in women of reproductive age, rarely in post-menopausal women and in women under 20 years of age.
Mazigo, Humphrey D, Seni, Jeremiah, Kombo, Hamis, Jaka, Hyasinta M, Faustine, Lucas, Zinga, Maria, Mshana, Stephen E, Mirambo, Mariam, Kabangila, Rodrick   +8 more
core  

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source

Primary Extragonadal Choriocarcinoma Presenting with Pneumothorax in an Elderly Male Patient: A Case Report

Case Reports in Oncology
Introduction: Choriocarcinoma is a highly malignant trophoblastic tumor and occurs exclusively as nongestational choriocarcinoma in male patients, which is extremely rare.
Hiroshi Shintani, Naoki Kataoka
doaj   +1 more source

A Successfully Treated Multiple Metastatic Choriocarcinoma Coexistent With Live Fetus: A Case Report and Literature Review

Frontiers in Oncology, 2022
Management of metastatic choriocarcinoma coexistent with live fetus is tricky for gynecologists. There is no consensus on treatment because of its rarity.
Wei Ding, Wei Ding, Na Zhang, Yang Rao, Xiaoning Xu, Tonggang Nie, Pengpeng Qu, Pengpeng Qu   +7 more
doaj   +1 more source

Diflubenzuron Caused Mitochondrial Dysfunction, Ca2+ Homeostasis Disruption, and Intrinsic Apoptosis in Trophoblastic Cells

Environmental Toxicology, EarlyView.
ABSTRACT Diflubenzuron is used as an insect growth inhibitor, and its potential risk to human health was raised owing to the possibility of environmental residues and human exposure. This study aimed to investigate the toxic mechanism of diflubenzuron on trophoblastic cells such as HTR8/SVneo and JEG‐3 cells. We investigated mitochondrial function, Ca2+
Miji Kim, Wonhyoung Park, Whasun Lim, Gwonhwa Song, Sunwoo Park   +4 more
wiley   +1 more source

Uterine choriocarcinoma coexistence with endometroid adenocacinoma: a case report and literature review

BMC Women's Health, 2023
Background Choriocarcinoma coexisting with endometrial carcinoma is rare. To the best of our knowledge, only one case of choriocarcinoma coexisting with endometrial carcinoma has been reported.
Liping Bai, Yali Chen, Ling Han, Ai Zheng, Xiaoyu Mo   +4 more
doaj   +1 more source

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source