Results 81 to 90 of about 23,159 (235)
Сибирский онкологический журнал, 2016 Choriocarcinoma is a malignant neoplasm arising usually from the placenta. It is characterized by early hematogenous metastasis. Due to early metastasis and chemoresistance, patients with choriocarcinoma may have a poor prognosis.
L. I. Kokh
doaj
Placental DEPTOR as a stress sensor during pregnancy [PDF]
, 2011 The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commercial use, distribution and ...
Gidron, Y +4 more
core +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend The human placenta not only detects the presence of Pb and Cd but also carries hypoxia and inflammatory risks, which are associated with pregnancy complications. To understand the impact of these factors on the placental trophoblast, we evaluated the effect of Pb and Cd on mitochondrial function and the NLRP3 inflammasome in ...
Yifeng Dai +4 more
wiley +1 more source
Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors [PDF]
, 2016 Background: Cisplatin (CDDP) resistance in testicular germ cell tumors (GCTs) is still a clinical challenge, and one associated with poor prognosis. The purpose of this work was to test pazopanib, an anti-tumoral and anti-angiogenic multikinase inhibitor,
Casanovas i Casanovas, Oriol +9 more
core +1 more source
Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell +3 more
wiley +1 more source
The Discovery, Use and Impact of Platinum Salts as Chemotherapy Agents for Cancer [PDF]
, 2007 Annotated and edited transcript of a Witness Seminar held on 4 April 2006. Introduction by Professor Matti Aapro, Grenolier, Switzerland.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2007.©The Trustee of the Wellcome ...
Christie, DA, Tansey, EM
core
Expression and importance of matrix metalloproteinase 2 and 9 (MMP-2 and -9) in human trophoblast invasion [PDF]
, 2004 Background The aim of this study was to examine the invasiveness of first trimester trophoblasts according to the secretion profile of MMP-2 and -9 at different gestational stages, and to test the similarity between primary trophoblast cell-culture and ...
Gabarin Diana +3 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Propionate in the fetal circulation is thought to originate from fermentation of dietary fibre by the maternal gut microbiota. However, the mechanism of transplacental transport has remained unclear. Here, we measured propionate permeability using a placental barrier model generated by differentiating human placental trophoblast ...
Toshiaki Tsuchitani +8 more
wiley +1 more source
Journal of Medical Case Reports, 2017 Background Gestational choriocarcinoma is the most common gestational trophoblastic neoplasia; it is often secondary to hydatidiform mole, as well as to abortion, ectopic pregnancy, premature delivery, or term delivery. Approximately 60% of patients with
Wenping Zhang +3 more
doaj +1 more source
Molecular genotyping of placental site and epithelioid trophoblastic tumours; female predominance [PDF]
, 2016 OBJECTIVE: To investigate a large series of placental site trophoblastic tumours (PSTT) and epithelioid trophoblastic tumours (ETT) and determine the relationship between their development and the type and sex of both the immediately antecedent and ...
Fisher, RA +4 more
core +1 more source