Results 121 to 130 of about 82,141 (253)

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida   +7 more
wiley   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

open access: yesBiological Reviews, Volume 101, Issue 5, Page 2265-2278, October 2026.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido   +2 more
wiley   +1 more source

Myasthenia Gravis and Thymoma

open access: yesMuscle &Nerve, Volume 74, Issue 4, Page 1156-1173, October 2026.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor   +5 more
wiley   +1 more source

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar   +3 more
wiley   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami   +15 more
wiley   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li   +9 more
wiley   +1 more source

Jacobs Syndrome Presenting With Delayed Puberty and Central Hypogonadism: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT In some rare instances, patients with 47,XYY syndrome can be short in height, accompanied by hypogonadism without the characteristic tall stature. In cases where there is delayed puberty and unusual growth pattern, a complete endocrine work‐up, including GnRH and hCG stimulation tests, along with chromosome studies, is vital.
Muhammad Hassaan Javaid   +4 more
wiley   +1 more source

Premature Ductus Arteriosus Constriction and Pulmonary Trunk Dilation in a Case of Non‐Immune Hydrops Fetalis With Trisomy 21

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Premature constriction of the ductus arteriosus accompanied by the dilation of the pulmonary trunk constitutes a rare congenital heart anomaly that may be underestimated and can result in fetal hydrops and ultimately death if not treated; therefore, it necessitates fetal post‐mortem evaluation in all cases of legal abortion or fetal death.
Nazari Mohadeseh   +2 more
wiley   +1 more source

Epigallocatechin Gallate From Tea Delays Oocyte Aging After Ovulation in Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 9, September 2026.
In this study, we find that EGCG delays post‐ovulatory oocyte aging and improves the quality of aged oocytes. EGCG may reduce ROS levels in aged oocytes by the NRF2‐KEAP1 pathway. The embryo developmental potential of aged oocytes is also increased by EGCG. ABSTRACT In clinic, once the ovulated oocytes cannot be fertilized timely, they begin to undergo
Jing Lin   +9 more
wiley   +1 more source

The Therapeutic Effects of Crocus sativus L. and Its Constituents on the Improving Treatment of Azoospermia: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Azoospermia, defined as the complete absence of sperm in the ejaculate, is a major cause of male infertility and is classified into obstructive and non‐obstructive forms. While obstructive azoospermia is primarily mechanical in origin, non‐obstructive azoospermia (NOA) is characterized by impaired spermatogenesis and is ...
Faraz Khakshour   +4 more
wiley   +1 more source

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