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Reduction of Testicular Human Chorionic Gonadotropin Receptors by Human Chorionic Gonadotropin in Infertile Men

Archives of Andrology, 1988
We measured testicular human chorionic gonadotropin (hCG) receptors in 30 infertile men either before or 1, 3, 5, 7, or 14 days after a single administration of 5000 IU of hCG. For 5 days the administration of hCG significantly reduced the testicular binding of 125I-hCG compared with that of the testes before administration.
Kunio Matsumoto   +8 more
openaire   +3 more sources

Chorionic Gonadotropin Tests for Diagnosis of Pregnancy and Chorionic Tumors

Postgraduate Medicine, 1969
Various chorionic gonadotropin tests (HCG) for the diagnosis of pregnancy and chorionic tumors are reviewed. The tests divide into biological and immunological groups. Immunological methods are generally more sensitive than biological methods. A brief description of the widely used hemagglutination inhibition and latex particle agglutination methods
Robert B. Greenblatt   +2 more
openaire   +3 more sources

Human chorionic gonadotropin tests

Expert Review of Molecular Diagnostics, 2009
Human chorionic gonadotropin (hCG) is not a single biological molecule. There is the regular form of hCG produced by differentiated syncytotrophoblast cells (regular hCG). This hormone primarily functions to maintain the myometrial and decidual spiral arteries, or the vascular supply of the placenta during the full course of pregnancy ...
openaire   +3 more sources

Expression of variant luteinizing hormone/chorionic gonadotropin receptors and degradation of chorionic gonadotropin in human chorionic villous macrophages

Placenta, 2005
Human gonads and non-gonadal organs/tissues express luteinizing hormone/chorionic gonadotropin (LH/CG) receptors. This study aimed to identify the LH/CG receptors and to clarify their function in human placental chorionic villous macrophages. Macrophages as well as syncytiotrophoblasts of human chorionic villous tissues were immunohistochemically ...
Takashi Ohba   +6 more
openaire   +3 more sources

Withholding Gonadotropins Until Human Chorionic Gonadotropin Administration

Seminars in Reproductive Medicine, 2010
Withholding gonadotropins in women who exhibit high estradiol responses before follicles reach full maturation is called "coasting." Coasting, or suspending gonadotropin administration, can be an effective strategy for decreasing the risk of ovarian hyperstimulation syndrome (OHSS) while reducing cancelation rates.
Isaac Kligman   +3 more
openaire   +3 more sources

Human Chorionic Gonadotropin

1973
Publisher Summary This chapter discusses human chorionic gonadotropin (HCG), the placental glycoprotein hormone. This hormone, produced by the cytotrophoblast, is comparable in biological action to pituitary luteinizing hormone (LH) or interstitial cell stimulating hormone (ICSH).
openaire   +2 more sources

Chorionic Gonadotropin in Rodents

1980
The nature of the luteotropic factor in rodent placentae has been a matter of controversy. Most textbooks in reproductive endocrinology claim that chorionic gonadotropin (CG) is found only in the human (hCG) and in some ape and monkey placentae, and that the luteotropic hormone in the rodent placenta is different, having both luteotropic and ...
Leif Wide, Bruce Hobson, Mariann Wide
openaire   +2 more sources

THE CYTOLOGICAL LOCALIZATION OF HUMAN CHORIONIC GONADOTROPIN

Canadian Journal of Biochemistry and Physiology, 1963
The indirect fluorescent antibody technique was used to determine the cellular site of human chorionic gonadotropin (H.C.G.) in normal and toxaemic placentas, and in choriocarcinomas. In placental tissue specific fluorescence was located in the syncytial cells of the chorionic villi but not in the cytotrophoblast cells.
Arthur Leznoff, Bernard A. Davis
openaire   +3 more sources

Human chorionic gonadotropin and malignant mesothelioma

Cancer, 1979
A 56-year-old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had ...
Stuart Rich   +5 more
openaire   +3 more sources

Carboxypeptidase Digestion of Human Chorionic Gonadotropin

Endocrine Research Communications, 1977
Native human chorionic gonadotropin (hCG) was resistant to carboxypeptidase digestion even in the presence of urea. Isolated alpha subunit of the hormone (hCG-alpha), though unreactive to enzyme treatment in the absence of denaturant, released up to four amino acid residues from the C-terminus on incubation with a mixture of carboxypeptidases A and B ...
V. G. Hum, H. G. Botting, K. F. Mori
openaire   +3 more sources

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