Use of the Abbott i‐STAT®1 point of care device for hCG quantification in early pregnancy
Abstract Objectives To evaluate the use of the Abbott i‐STAT®1 point‐of‐care‐test (POCT) device for measurement of human chorionic gonadotropin (hCG) to support the management of early pregnancy complications in a remote early pregnancy unit (EPU). Methods Women attending the EPU who required an hCG blood test were invited to take part in the study ...
Caroline Joyce+7 more
wiley +1 more source
Update on male reproductive endocrinology. [PDF]
Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
core +1 more source
Adverse Effects of Trichothiodystrophy DNA Repair and Transcription Gene Abnormalities on Human Fetal Development [PDF]
The effects of DNA repair and transcription genes in human prenatal life have never been studied. Trichothiodystrophy (TTD) is a rare (affected frequency of 10^-6^) recessive disorder caused by mutations in genes involved in the nucleotide excision ...
Amiran Dzutsev+4 more
core +2 more sources
SYN expression in patients with gastric cancer is correlated with the degree of differentiation and Lauren's typing. The prognosis of SYN‐positive gastric cancer patients is worse than that of SYN‐negative patients. ABSTRACT Background This study aims to determine prognostic indicators of synaptophysin (SYN) positive gastric cancer with neuroendocrine ...
Xuemei Wei+4 more
wiley +1 more source
Mechanism for long-acting chimeras based on fusion with the carboxyl-terminal peptide (CTP) of human chorionic gonadotropin beta-subunit 3 [PDF]
Thermodynamic scaling explains the dramatic successes of CTP fused human growth proteins as regards lifetime in vivo and enhanced functionality compared to their wild-type analogues, like Biogen. The theory is semi-quantitative and contains no adjustable parameters.
arxiv
Tandem duplications and the limits of natural selection in Drosophila yakuba and Drosophila simulans [PDF]
Tandem duplications are an essential source of genetic novelty, and their variation in natural populations is expected to influence adaptive walks. Here, we describe evolutionary impacts of recently-derived, segregating tandem duplications in Drosophila yakuba and Drosophila simulans. We observe an excess of duplicated genes involved in defense against
arxiv +1 more source
The free β-subunit of human chorionic gonadotropin as a prognostic factor in renal cell carcinoma [PDF]
The free β-subunit of human chorionic gonadotropin β is expressed in several nontrophoblastic tumours and this is usually associated with aggressive disease. Little is known about human chorionic gonadotropin β expression in renal cancer.
A Paju+32 more
core +2 more sources
Mouse versus Rat: Profound Differences in Meiotic Regulation at the Level of the Isolated Oocyte [PDF]
Cumulus cell-enclosed oocytes (CEO), denuded oocytes (DO), or dissected follicles were obtained 44–48 hr after priming immature mice (20–23 days old) with 5 IU or immature rats (25–27 days old) with 12.5 IU of equine chorionic gonadotropin, and exposed ...
Biggers+61 more
core +2 more sources
Integrating Surface‐Enhanced Raman Scattering (SERS) with machine learning creates a powerful platform for cancer management. This approach enhances diagnostic precision through non‐invasive molecular fingerprinting and enables real‐time therapeutic monitoring. By combining SERS with machine learning, it offers a comprehensive solution for early cancer
Heng‐Zhou He+9 more
wiley +1 more source
Organization and sequence of the gene encoding the human acrosin-trypsin inhibitor (HUSI-II) [PDF]
A complete cDNA encoding the acrosin-trypsin inhibitor, HUSI-II, was used as a probe to isolate genomic clones from a human placenta library. Three clones which cover the entire HUSI-II gene were isolated and characterized.
Abelson+28 more
core +1 more source