Results 91 to 100 of about 45,363 (196)
The Journal of Physiology, EarlyView.Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Kathryn Wilsterman +6 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend New approach methodologies (NAMs) to test the pharmaco‐ and chemicokinetics of compound transfer across the human placental barrier in late pregnancy. Abstract This review addresses an important and timely topic at the intersection of placental biology with respect to barrier transfer kinetics, toxicology and mathematical ...
Paul Brownbill, Eleanor Doman
wiley +1 more source
Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell +3 more
wiley +1 more source
Comparision of telomerase activity in human chorionic villi between eutopic and ectopic pregnancies
, 2000 Objectives : To compare the presence of telomerase activity(TA) in the chorionic villi between eutopic and ectopic first trimester human pregnancies. Methods : Human chorionic villi were obtained from eleven normal eutopic pregnant women who underwent an
정현철, 배상욱, 김세광
core
, 2022 AimNo definite conclusions have been drawn regarding how prolonged exposure to hyperglycemia affects the distribution of macrophages in the placenta, especially in pregnant women with uncontrolled type 2 diabetes mellitus (T2DM).
Dong Cui (1435516) +2 more
core +1 more source
Physiological and anatomical determinants of placental drug transfer
The Journal of Physiology, EarlyView.Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis +3 more
wiley +1 more source
First-trimester diagnosis on chorionic villi obtained by direct vision technique
, 1984 An improved technique for direct vision chorionic biopsy that gives a clear view of the amniotic sac was developed. With this technique, used in 48 women prior to vacuum aspiration and in six cases for diagnosis (karyotyping or enzyme analysis), it was ...
Mineur, Anita +12 more
core +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida +7 more
wiley +1 more source
Distribution of CA 125 in Placental Tissues
The International Journal of Biological Markers, 1989 The presence of the tumor marker CA 125 was studied in different compartments of the human placenta. Levels of CA 125 in the cytosol of chorionic villi ranged from 27 - 17100 U/g (median 560 U/g). In the placental amnion and chorion concentrations ranged
L.C. Fuith +5 more
doaj +1 more source