Results 81 to 90 of about 42,724 (240)

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell, Andrew C. Povey, Edward D. Johnstone, Peter T. Ruane   +3 more
wiley   +1 more source

Chorionic Villi Sampling: A Nursing Perspective

Journal of Obstetric, Gynecologic & Neonatal Nursing, 1988
A relatively new procedure, chorionic villi sampling is now available as an alternative method for prenatal diagnoses of genetic disorders during pregnancy. Indications, procedures, risks, advantages, and nursing implications of this procedure are defined and described.
openaire   +2 more sources

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source

aCGH on chorionic villi mirrors the complexity of fetoplacental mosaicism in prenatal diagnosis

, 2011
To describe the diagnostic performance of array comparative genomic hybridization (aCGH) in the presence of mosaicism in the fetoplacental unit using direct chorionic ...
Anjeung Kang, Sevgi Tercanli, Heinimann, Karl, Tercanli, Sevgi, Filges, Isabel, Vanessa Klug, Miny, Peter, Klug, Vanessa, Karl Heinimann, Wenzel, Friedel, Isabel Filges, Friedel Wenzel, Peter Miny, Kang, Anjeung   +13 more
core   +1 more source

Image3_Case report: Prenatal diagnosis of rare chromosome mosaicism: discordant results between chorionic villi and amniotic fluid samples.jpg

, 2023
Objective: We described a unique case of near-negative chromosome mosaicism in chorionic villi but complete monosomy X in amniotic fluid.Methods: Chorionic villus sampling and amniocentesis were performed separately in the first and second trimesters ...
He Wang (250350), Shanling Liu (11257638), Hongmei Zhu (105489), Xuemei Zhang (89768), Xijing Liu (16021871), Qinqin Li (2023468), Lili Zhang (120447), Yueyue Xiong (16021874), Lingping Li (5558414)   +8 more
core   +1 more source

Global Recommendations for the Use of Diagnostic Genomic Sequencing in the Prenatal Setting on Behalf of the ESHG and ISPD

Prenatal Diagnosis, EarlyView.
Zandra C. Deans, Lina Basel Salmon, Kwong Wai Choy, Guido de Wert, Zirui Dong, Lilian Downie, Francesca Romana Grati, Sabine Hentze, Paula Jorge, Brynn Levy, Luca Lovrecic, Dora Mayen, Álvaro Mendes, Michael Morris, Ashley Pritchard, Raquel Gouveia Silva, Tina‐Marié Wessels, Francesca Forzano, Natalie J. Chandler   +18 more
wiley   +1 more source

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida, Nadja Koechli, Edgar Ontsouka, Chennakesava Cuddapah, Martin Mueller, Bram Sengers, Frantisek Staud, Christiane Albrecht   +7 more
wiley   +1 more source

Localization of Chorionic Gonadotropin in Macrophages of the Human Chorionic Villi

Endocrine Journal, 1994
Peculiar mononuclear cells existing in the mesenchymal stroma of human chorionic villi, termed Hofbauer cells, are macrophages, and they are characterized by many vacuoles of various sizes and small granules in the cytoplasm. Their functional properties are still a matter of controversy.
KATABUCHI, HIDETAKA, FUKUMATSU, YUKITOSHI, ARAKI, MASAKO, MIZUTANI, HIROSHI, OHBA, TAKASHI, OKAMURA, HITOSHI   +5 more
openaire   +2 more sources

Image2_Case report: Prenatal diagnosis of rare chromosome mosaicism: discordant results between chorionic villi and amniotic fluid samples.jpg

, 2023
Objective: We described a unique case of near-negative chromosome mosaicism in chorionic villi but complete monosomy X in amniotic fluid.Methods: Chorionic villus sampling and amniocentesis were performed separately in the first and second trimesters ...
He Wang (250350), Shanling Liu (11257638), Hongmei Zhu (105489), Xuemei Zhang (89768), Xijing Liu (16021871), Qinqin Li (2023468), Lili Zhang (120447), Yueyue Xiong (16021874), Lingping Li (5558414)   +8 more
core   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source