Results 61 to 70 of about 12,464 (192)

Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum, Catherine Lee, Tippi MacKenzie, Billie Lianoglou, Agnieszka Czechowicz   +4 more
wiley   +1 more source

Image6_Case report: Prenatal diagnosis of rare chromosome mosaicism: discordant results between chorionic villi and amniotic fluid samples.jpg

, 2023
Objective: We described a unique case of near-negative chromosome mosaicism in chorionic villi but complete monosomy X in amniotic fluid.Methods: Chorionic villus sampling and amniocentesis were performed separately in the first and second trimesters ...
He Wang (250350), Qinqin Li, He Wang, Shanling Liu (11257638), Xuemei Zhang (89768), Qinqin Li (2023468), Xijing Liu, Lili Zhang, Yueyue Xiong, Shanling Liu, Xuemei Zhang, Hongmei Zhu (105489), Xijing Liu (16021871), Lili Zhang (120447), Hongmei Zhu, Lingping Li, Yueyue Xiong (16021874), Lingping Li (5558414)   +17 more
core   +1 more source

Confocal Laser Scanning Microscopy and Chorionic Term Villi

Journal of Biological Research, 2003
The confocal laser scanning microscopy (CLSM) is a relative new biomedical technology and represents a good alternative to the conventional optical microscopy in the observation of static and dynamics events. CLSM is able to produce 3-dimensional images
C. Capobianco, L. Resta, G. I. D'Antona, A. Marzullo, D. Piscitelli, L. Gesualdo   +5 more
doaj   +1 more source

Evaluating the Utility of RNAseq in Prenatal Diagnostics: Expression Profiles of Cultured Chorionic Villus and Amniotic Fluid Samples

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective While RNAseq has enhanced variant interpretation in postnatal cases, its potential in the prenatal setting remains underexplored. This study investigates the utility of RNAseq in prenatal diagnostics by analyzing the expression profiles of cultured chorionic villus samples (cCVS) and amniotic fluid (cAF) samples. Methods We performed
Maria C. Vladoiu, Sen Zhao, Roni Zemet, Christian M. Parobek, Jefferson Cruz Sinson, Stacy Tankersley, Ignatia B. Van den Veyver, Pengfei Liu   +7 more
wiley   +1 more source

Role of matrix metalloproteinases 2 and 9 in ex vivo Trypanosoma cruzi infection of human placental chorionic villi [PDF]

, 2012
Background: Chagas' disease is caused by the haemophlagelated protozoan Trypanosoma cruzi (T. cruzi). During congenital transmission the parasite breaks down the placental barrier.
Cabrera, G., Maya Arango, Juan, Duaso, J., Castillo, C., Galanti Garrone, Norbel, Jaña, F., Kemmerling Weis, Ulrike, López-Muñoz, R., Ferreira, J.   +8 more
core   +1 more source

Image1_Case report: Prenatal diagnosis of rare chromosome mosaicism: discordant results between chorionic villi and amniotic fluid samples.jpg

, 2023
Objective: We described a unique case of near-negative chromosome mosaicism in chorionic villi but complete monosomy X in amniotic fluid.Methods: Chorionic villus sampling and amniocentesis were performed separately in the first and second trimesters ...
He Wang (250350), Shanling Liu (11257638), Hongmei Zhu (105489), Xuemei Zhang (89768), Xijing Liu (16021871), Qinqin Li (2023468), Lili Zhang (120447), Yueyue Xiong (16021874), Lingping Li (5558414)   +8 more
core   +1 more source

Molecular Insights into the Thrombotic and Microvascular Injury in Placental Endothelium of Women with Mild or Severe COVID-19

Cells, 2021
Clinical manifestations of coronavirus disease 2019 (COVID-19) in pregnant women are diverse, and little is known of the impact of the disease on placental physiology.
Arturo Flores-Pliego, Jael Miranda, Sara Vega-Torreblanca, Yolotzin Valdespino-Vázquez, Cecilia Helguera-Repetto, Aurora Espejel-Nuñez, Héctor Borboa-Olivares, Salvador Espino y Sosa, Paloma Mateu-Rogell, Moisés León-Juárez, Victor Ramírez-Santes, Arturo Cardona-Pérez, Isabel Villegas-Mota, Johnatan Torres-Torres, Ángeles Juárez-Reyes, Thelma Rizo-Pica, Rosa O. González, Lorenza González-Mariscal, Guadalupe Estrada-Gutierrez   +18 more
doaj   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Image5_Case report: Prenatal diagnosis of rare chromosome mosaicism: discordant results between chorionic villi and amniotic fluid samples.jpg

, 2023
Objective: We described a unique case of near-negative chromosome mosaicism in chorionic villi but complete monosomy X in amniotic fluid.Methods: Chorionic villus sampling and amniocentesis were performed separately in the first and second trimesters ...
He Wang (250350), Shanling Liu (11257638), Hongmei Zhu (105489), Xuemei Zhang (89768), Xijing Liu (16021871), Qinqin Li (2023468), Lili Zhang (120447), Yueyue Xiong (16021874), Lingping Li (5558414)   +8 more
core   +1 more source

Prenatal sex determination in suspicious cases of X-linked recessive diseases by the amelogenin gene [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s):To determine the fetal discernment in suspected cases of sex linked recessive disease in the first trimester of pregnancy. Materials and Methods: After collection of 100 Chorionic Villi samples, the DNAs were extracted and baby gender was ...
Amir Abbas Rahimi, Mohammad Hassan Shahhosseiny, Ghasem Ahangari, Jalal Izadi Mobarakeh   +3 more
doaj