Results 51 to 60 of about 45,363 (196)

Medical abortion in the first trimester of pregnancy, complicated by ingrown chorionic villi

Фундаментальная и клиническая медицина
Chorionic villi ingrowth is a serious complication of pregnancy, which is a common cause of maternal mortality and postpartum hysterectomy. The prevalence of this pathological condition has increased significantly over the past 30 years due to an ...
G. Yu. Gulnyashkina, G. I. Kolpinskiy, O. G. Lobanova, E. P. Sokolova   +3 more
doaj   +1 more source

Triploidy--Observations in 154 Diandric Cases. [PDF]

PLoS ONE, 2015
Hydatidiform moles (HMs) are abnormal human pregnancies with vesicular chorionic villi, imposing two clinical challenges; miscarriage and a risk of gestational trophoblastic neoplasia (GTN).
Nanna Brink Scholz, Lars Bolund, Mette Nyegaard, Louise Faaborg, Mette Warming Jørgensen, Helle Lund, Isa Niemann, Lone Sunde   +7 more
doaj   +1 more source

Chorionic Structures in Maternal Blood [PDF]

, 2007
Chorionic villi are the exchange structures of the placenta where human fetuses receive oxygen and nutrients from maternal blood, this article reports an improvement of a published method to recover them from the blood of pregnant, women, quotes their ...
Nilo Pereira Luz
core  

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source

Localization of matrix metalloproteinases in the placenta of cows with complicated pregnancy by placental insufficiency [PDF]

BIO Web of Conferences
The placenta of 8 cows with physiological (PP) and placental insufficiency pregnancy (FPI) served as the material for the study. Analysis of the content of glycosaminoglycans (GAG) in the tissue of the uterine part of the placenta in cows with FPI ...
Avdeenko V.S., Safronov D.I., Akhmadov V.T.   +2 more
doaj   +1 more source

Number of fully informative loci in 152 (near) triploid cases with vesicular chorionic villi, analyzed along with a maternal sample.

, 2015
Number of fully informative loci in 152 (near) triploid cases with vesicular chorionic villi, analyzed along with a maternal sample.
Helle Lund (825577), Nanna Brink Scholz (825574), Mette Warming Jørgensen (825576), Lone Sunde (547072), Louise Faaborg (825575), Mette Nyegaard (202075), Lars Bolund (14173), Isa Niemann (825578)   +7 more
core   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

Advanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu, Lingling Xie, Wenyi Liu, Hanjie Mo, Chengshu Xie, Jing Tang, Zhaorui Wang, Peixuan Lan, Jianping Zhang, Jie Gao, Qionglan Tang, Chunwei Cao, Hui Chen   +12 more
wiley   +1 more source

High Diagnosis Rate for Nonimmune Hydrops Fetalis With Prenatal Clinical Genome: Expanded Results From the Hydrops‐Yielding Diagnostic Results of Prenatal Sequencing (HYDROPS) Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nonimmune hydrops fetalis (NIHF) is characterized by abnormal fluid accumulation in ≥ 2 fetal compartments and may be genetic. The incremental diagnostic yield of prenatal exome sequencing (ES) for NIHF following a negative standard workup was previously explored on 22 cases.
Stephanie M. Rice, Mona M. Makhamreh, Sascha Wodoslawsky, Mariella Toro, Elizabeth Critchlow, Brandy Firman, Ruby Liu, Babi Ramesh Nallamilli, Madhuri Hegde, Seth I. Berger, Huda B. Al‐Kouatly   +10 more
wiley   +1 more source

Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability

Cells, 2019
The cytotrophoblast of human placenta transitions into an outer multinucleated syncytiotrophoblast (STB) layer that covers chorionic villi which are in contact with maternal blood in the intervillous space. During pregnancy, the Zika virus (ZIKV) poses a
Jael Miranda, Dolores Martín-Tapia, Yolotzin Valdespino-Vázquez, Lourdes Alarcón, Aurora Espejel-Nuñez, Mario Guzmán-Huerta, José Esteban Muñoz-Medina, Mineko Shibayama, Bibiana Chávez-Munguía, Guadalupe Estrada-Gutiérrez, Samuel Lievano, Juan Ernesto Ludert, Lorenza González-Mariscal   +12 more
doaj   +1 more source