Results 41 to 50 of about 42,724 (240)

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen, Li Gao, Xu Han, Yunyun Cao, Lanlan Zhang, Yi Wu, Xinrong Zhao, Wenjing Hu, Ruiyu Ma, Renyi Hua, Niu Li, Yanlin Wang, Jian Wang, Shuyuan Li   +13 more
wiley   +1 more source

Localization of matrix metalloproteinases in the placenta of cows with complicated pregnancy by placental insufficiency [PDF]

BIO Web of Conferences
The placenta of 8 cows with physiological (PP) and placental insufficiency pregnancy (FPI) served as the material for the study. Analysis of the content of glycosaminoglycans (GAG) in the tissue of the uterine part of the placenta in cows with FPI ...
Avdeenko V.S., Safronov D.I., Akhmadov V.T.   +2 more
doaj   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

Clinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung, Nicholas Ieronimakis, Bothaina Mousa, Emily D. Sheikh, Sarah E. Ligon, Joshua W. Monson, Jennifer R. Damicis, Hillary J. Kinsman, Lydia E. Bettridge, Samuel L.M. Arnold, Edward J. Kelly, Jashvant D. Unadkat, Joanne Wang   +12 more
wiley   +1 more source

Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability

Cells, 2019
The cytotrophoblast of human placenta transitions into an outer multinucleated syncytiotrophoblast (STB) layer that covers chorionic villi which are in contact with maternal blood in the intervillous space. During pregnancy, the Zika virus (ZIKV) poses a
Jael Miranda, Dolores Martín-Tapia, Yolotzin Valdespino-Vázquez, Lourdes Alarcón, Aurora Espejel-Nuñez, Mario Guzmán-Huerta, José Esteban Muñoz-Medina, Mineko Shibayama, Bibiana Chávez-Munguía, Guadalupe Estrada-Gutiérrez, Samuel Lievano, Juan Ernesto Ludert, Lorenza González-Mariscal   +12 more
doaj   +1 more source

Designing Effective Multi-Target Drugs and Identifying Biomarkers in Recurrent Pregnancy Loss (RPL) Using In Vivo, In Vitro, and In Silico Approaches

Biomedicines, 2023
Recurrent pregnancy loss (RPL) occurs in approximately 5% of women. Despite an abundance of evidence, the molecular mechanism of RPL’s pathology remains unclear. Here, we report the protective role of polo-like kinase 1 (PLK1) during RPL.
Andrés Alexis Ramírez-Coronel, Amirabbas Rostami, Laith A. Younus, José Luis Arias Gonzáles, Methaq Hadi Lafta, Ali H. Amin, Mohammed Abdulkadhim Saadoon, Hayder Mahmood Salman, Abolfazl Bahrami, Rossa Feilei, Reza Akhavan-Sigari   +10 more
doaj   +1 more source

Generation of iPSC lines from primary human chorionic villi cells [PDF]

, 2015
Primary human chorionic villi (CV) cells were used to generate the iPSC line by retroviral transduction of the four Yamanaka-factors OCT4, SOX2, KLF4 and c-MYC. Pluripotency was confirmed both in vivo and in vitro.
Björn Lichtner, James Adjaye, Matz, Peggy, Adjaye, James, Lichtner, Björn, Peggy Matz   +5 more
core   +1 more source

Vaginal host–microbe signatures linked to placental outcomes in mares

Equine Veterinary Journal, EarlyView.
Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule, Babiche Heil, Jamie K. Norris, Kristene Gedye, Xiaoxiao Lin, Ward De Spiegelaere, Peter Daels, Pouya Dini   +7 more
wiley   +1 more source

Mesenchymal tissue of the chorionic plate and villi infected with ZIKV at 10 dpi.

, 2023
(A) full slide evaluated with ISH shown as pink staining. The orange square outlines the area of the slide magnified in portion (B). (B) CP indicates chorionic plate. The black square outlines the portion of the slide magnified in (C–E).
Julia C. Pritchard (14851810), Thaddeus G. Golos (3375128), Ellie K. Bohm (10807791), Eva Winston (16793032), Puja Basu (13200531), Terry K. Morgan (4807350), Heather A. Simmons (8259912), Emma L. Mohr (3375131), Michelle R. Koenig (4538368), Fernanda B. Leyva Jaimes (16793029), Leticia Reyes (105757), Emily Ren (16793026), Andrea M. Weiler (9553607), Jenna A. Schmidt (16793023), Ann M. Mitzey (4624045), Xiankun Zeng (623049), Thomas C. Friedrich (8321406), Matthew T. Aliota (9519647)   +17 more
core   +1 more source

Membranous dysmenorrhea and decidual casts: A scoping review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Membranous dysmenorrhea, characterized by the expulsion of intact endometrial tissue rather than gradual dissolution during menstruation, occasionally presents as a decidual cast—a complete triangular mold of the uterine cavity. This poorly understood condition is likely underdiagnosed.
Lovisa Brehmer, Hedvig Engberg
wiley   +1 more source

MORPHOMETRIC PARAMETERS OF PLACENTAL CHORIONIC VILLI IN LABOR AFTER 40 WEEKS

Неонатологія, хірургія та перинатальна медицина
The placenta is the main organ that ensures the vital activity of the fetus during pregnancy. Studying the morphometric characteristics of chorionic villi allows us to better understand the changes that occur in the placenta in late pregnancy.
О. Козар
doaj   +1 more source