Results 51 to 60 of about 2,656 (193)

DETERMINATION OF FETAL RHESUS D STATUS BY MATERNAL PLASMA DNA ANALYSIS

Balkan Journal of Medical Genetics, 2013
In this study, we assessed the feasibility of fetal RhD genotyping by analysis of cell-free fetal DNA(cffDNA) extracted from plasma samples of Rhesus (Rh) D-negative pregnant women by using real-time polymerase chain reaction (PCR).
Aykut A., Onay H., Gunduz C., Ozkinay F., Cogulu O., Sagol S.   +5 more
doaj   +1 more source

Sex differences in the late first trimester human placenta transcriptome

Biology of Sex Differences, 2018
Background Development of the placenta during the late first trimester is critical to ensure normal growth and development of the fetus. Developmental differences in this window such as sex-specific variation are implicated in later placental disease ...
Tania L. Gonzalez, Tianyanxin Sun, Alexander F. Koeppel, Bora Lee, Erica T. Wang, Charles R. Farber, Stephen S. Rich, Lauren W. Sundheimer, Rae A. Buttle, Yii-Der Ida Chen, Jerome I. Rotter, Stephen D. Turner, John Williams, Mark O. Goodarzi, Margareta D. Pisarska   +14 more
doaj   +1 more source

The Clinical Utility of Sequence‐Based Genetic Testing for Fetal Edema Following Non‐Diagnostic Microarray Results: A Population‐Based Cohort Study

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Ultrasound findings of fetal edema may provide early evidence of a genetic disorder. Our objective was to evaluate the frequency and diagnostic yield of sequencing in a selected population after a non‐diagnostic microarray result for fetal edema.
Victoria M. Allen, Heleen H. Arts, Erica Schollenberg, Samantha Kinley, Erika Aberg, Jo‐Ann K. Brock   +5 more
wiley   +1 more source

Risk of Placental Pathology Across Ultrasound‐Defined Phenotypes of Impaired Fetal Growth in Dichorionic Twins: A Retrospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To determine the risk of placental dysfunction associated with different ultrasound‐based phenotypes of impaired fetal growth in dichorionic twin pregnancies. Design Retrospective cohort study. Setting Single tertiary centre. Population Patients with dichorionic twin pregnancies delivered at ≥ 320/7 (2011–2023) (N = 753).
Ala Essalah, John Kingdom, Liran Hiersch, Jon Barrett, Megan Watson, Nir Melamed   +5 more
wiley   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

A feasible strategy of preimplantation genetic diagnosis for carriers with chromosomal translocation: Using blastocyst biopsy and array comparative genomic hybridization

Journal of the Formosan Medical Association, 2013
Patients with chromosomal translocation are highly vulnerable to produce unbalanced gametes that result in recurrent miscarriages, affected offspring, or infertility.
Chu-Chun Huang, Li-Jung Chang, Yi-Yi Tsai, Chia-Cheng Hung, Mei-Ya Fang, Yi-Ning Su, Hsin-Fu Chen, Shee-Uan Chen   +7 more
doaj   +1 more source

Discrepancy in menstrual and ultrasound‐based gestational age is associated with chromosomal aberrations and adverse pregnancy outcomes—Results from a nationwide cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
A smaller than expected crown–rump length (CRL) relative to last menstrual period was strongly associated with increased risk of chromosomal abnormalities, adverse pregnancy outcomes, and obstetric complications. Conversely, a larger than expected CRL was associated with a reduced risk of these outcomes.
Simone Hansen, Olav Bjørn Petersen, Ida Vogel, Nina Gros Pedersen, Lars Henning Pedersen, Steffen Ernesto Kristensen, Karin Sundberg, Emilie Thorup, Cathrine Vedel, Kasper Gadsbøll   +9 more
wiley   +1 more source

The prevalence of SMN gene deletion/duplication in spinal muscular atrophy families referred to neuro-genetic centers of Mashhad, Iran

Egyptian Journal of Medical Human Genetics
Background Spinal muscular atrophy (SMA) is a group of motor neuron diseases. In 95% of SMA patients, the telomeric copy of the SMN gene (SMN1) is homozygously deleted.
Mohammad Shariati, Alireza Davoudi, Reza Boostani, Farah Ashrafzadeh, Mehran Beiraghi Toosi, Nafiseh Todarbary, Javad Akhondian, Narges Hashemi, Ariane Sadr-Nabavi   +8 more
doaj   +1 more source

Perinatal outcomes of expectant management versus fetal reduction in triplet pregnancies: A single‐center retrospective cohort study in Korea

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Our findings highlight that adverse outcomes, including early fetal loss, preterm birth, and peripartum complications, remain frequent in the natural course of triplet gestations. Fetal reduction, when considered in the context of triplet pregnancies, appears to be a relatively safe procedure and may be discussed as a management option in selected ...
Yoo Jin Lee, Jin Hoon Chung, Jae Yi Jeong, Jihye Koh, Mi‐Young Lee, Hye‐Sung Won   +5 more
wiley   +1 more source

Placental pathology in gestational diabetes mellitus: Associations with neonatal outcomes and postpartum dysglycemia

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Gestational diabetes mellitus is associated with increased placental vascular and villous lesions compared with normoglycemic pregnancies. Distal villous immaturity was linked to adverse neonatal outcomes, while chorangiosis predicted postpartum maternal dysglycemia, highlighting the placenta as a marker of both neonatal risk and future maternal ...
Chutima Chavanisakun, Siriwan Tangjitgamol, Chadakarn Phaloprakarn   +2 more
wiley   +1 more source