Results 91 to 100 of about 13,676 (200)

The Clinical Utility of Sequence‐Based Genetic Testing for Fetal Edema Following Non‐Diagnostic Microarray Results: A Population‐Based Cohort Study

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Ultrasound findings of fetal edema may provide early evidence of a genetic disorder. Our objective was to evaluate the frequency and diagnostic yield of sequencing in a selected population after a non‐diagnostic microarray result for fetal edema.
Victoria M. Allen, Heleen H. Arts, Erica Schollenberg, Samantha Kinley, Erika Aberg, Jo‐Ann K. Brock   +5 more
wiley   +1 more source

Risk of Placental Pathology Across Ultrasound‐Defined Phenotypes of Impaired Fetal Growth in Dichorionic Twins: A Retrospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To determine the risk of placental dysfunction associated with different ultrasound‐based phenotypes of impaired fetal growth in dichorionic twin pregnancies. Design Retrospective cohort study. Setting Single tertiary centre. Population Patients with dichorionic twin pregnancies delivered at ≥ 320/7 (2011–2023) (N = 753).
Ala Essalah, John Kingdom, Liran Hiersch, Jon Barrett, Megan Watson, Nir Melamed   +5 more
wiley   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

Generation of an induced pluripotent stem cell line from chorionic villi of a Patau syndrome spontaneous abortion

Stem Cell Research, 2020
Patau syndrome is a rare congenital malformation syndrome due to the presence of an extra chromosome 13. In this paper, we report the generation of an induced pluripotent stem cell line from the fibroblasts isolated from chorionic villi of an early ...
Ping Long, Zheng Liu, Bangyong Wu, Jingxi Chen, Chao Sun, Fei Wang, Yuanhua Huang, Hongjian Chen, Qi Li, Yanlin Ma   +9 more
doaj   +1 more source

Discrepancy in menstrual and ultrasound‐based gestational age is associated with chromosomal aberrations and adverse pregnancy outcomes—Results from a nationwide cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
A smaller than expected crown–rump length (CRL) relative to last menstrual period was strongly associated with increased risk of chromosomal abnormalities, adverse pregnancy outcomes, and obstetric complications. Conversely, a larger than expected CRL was associated with a reduced risk of these outcomes.
Simone Hansen, Olav Bjørn Petersen, Ida Vogel, Nina Gros Pedersen, Lars Henning Pedersen, Steffen Ernesto Kristensen, Karin Sundberg, Emilie Thorup, Cathrine Vedel, Kasper Gadsbøll   +9 more
wiley   +1 more source

Genetic testing in Marfan syndrome [PDF]

, 2016
Genetic testing is aiding rapid diagnosis of Marfan syndrome as a basis for management of eye, heart and skeletal disease. The affected patient's mutation can be used as a basis for prenatal or postnatal diagnosis of offspring.
Aragon-Martin, JA, Child, AH, Sage, K
core   +1 more source

Placenta accreta spectrum and uterine SCAR dehiscence: Distinct entities or a continuum? An expert debate and call for standardization

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This review explores the ongoing debate on whether placenta accreta spectrum and uterine scar dehiscence are distinct entities or part of a continuum. It discusses diagnostic challenges, surgical implications, and clinical consequences, emphasizing how misclassification may affect counseling, operative strategy, and outcomes, and calling for clearer ...
Theophilus Adu‐Bredu, Rozi Aditya Aryananda, Sarah P. Walker, Yaw Gyanteh Owusu, Thorsten Braun, Hooman Soleymani majd, Pedro Viana Pinto, Olivier Morel, Abdalla Mousa, Helena C. Bartels, Ammar Al Naimi, Maddalena Morlando, Karin A. Fox, Sally L. Collins   +13 more
wiley   +1 more source

Perinatal outcomes of expectant management versus fetal reduction in triplet pregnancies: A single‐center retrospective cohort study in Korea

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Our findings highlight that adverse outcomes, including early fetal loss, preterm birth, and peripartum complications, remain frequent in the natural course of triplet gestations. Fetal reduction, when considered in the context of triplet pregnancies, appears to be a relatively safe procedure and may be discussed as a management option in selected ...
Yoo Jin Lee, Jin Hoon Chung, Jae Yi Jeong, Jihye Koh, Mi‐Young Lee, Hye‐Sung Won   +5 more
wiley   +1 more source

Placental pathology in gestational diabetes mellitus: Associations with neonatal outcomes and postpartum dysglycemia

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Gestational diabetes mellitus is associated with increased placental vascular and villous lesions compared with normoglycemic pregnancies. Distal villous immaturity was linked to adverse neonatal outcomes, while chorangiosis predicted postpartum maternal dysglycemia, highlighting the placenta as a marker of both neonatal risk and future maternal ...
Chutima Chavanisakun, Siriwan Tangjitgamol, Chadakarn Phaloprakarn   +2 more
wiley   +1 more source

Chorionic Villus Sampling

Journal of Fetal Medicine, 2017
AbstractChorionic villus sampling (CVS) is a form of prenatal diagnosis to determine chromosomal or genetic disorders in the fetus. It entails sampling of the chorionic villus (placental tissue) and testing it for chromosomal abnormalities. It usually takes place at 10–12 weeks’ gestation, earlier than amniocentesis or percutaneous umbilical cord blood
openaire   +1 more source