Case report: Prenatal diagnosis of rare chromosome mosaicism: discordant results between chorionic villi and amniotic fluid samples [PDF]
Frontiers in Genetics, 2023 Objective: We described a unique case of near-negative chromosome mosaicism in chorionic villi but complete monosomy X in amniotic fluid.Methods: Chorionic villus sampling and amniocentesis were performed separately in the first and second trimesters ...
Lingping Li +26 more
doaj +4 more sources
Characteristic DNA methylation profiles of chorionic villi in recurrent miscarriage [PDF]
Scientific Reports, 2022 Dysregulation of transcriptional programs that are tightly regulated by DNA methylation during placental and fetal development at different gestational stages, may cause recurrent miscarriage.
Yosuke Matsumoto +13 more
doaj +2 more sources
Chorionic Villi Sampling [PDF]
Journal of Medical Genetics, 1987 The cytogenetic findings were analysed in a series of 500 pregnancies in which chorionic villi sampling was performed. In all cases a direct method was used, karyotyping being successful in 481 cases (96.2%). The main indication for sampling was maternal age over 36 (412 cases; 82.4%).
Louise Giles, Paul Donnai
core +6 more sources
The Distributional Characteristics of M2 Macrophages in the Placental Chorionic Villi are Altered Among the Term Pregnant Women With Uncontrolled Type 2 Diabetes Mellitus [PDF]
Frontiers in Immunology, 2022 AimNo definite conclusions have been drawn regarding how prolonged exposure to hyperglycemia affects the distribution of macrophages in the placenta, especially in pregnant women with uncontrolled type 2 diabetes mellitus (T2DM).
Muqiu Zhang, Dong Cui, Huixia Yang
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Metabolomic Investigation of β-Thalassemia in Chorionic Villi Samples [PDF]
Journal of Clinical Medicine, 2019 Beta-thalassemias are blood disorders characterized by poorly understood clinical phenotypes ranging from asymptomatic to severe anemia. Metabolic composition of the human placenta could be affected by the presence of pathological states such as β ...
Luigi Atzori +2 more
exaly +4 more sources
Pregnancy Outcome and Postnatal Chromosome Analysis of the Cord Blood and Chorionic Villi in Two Cases after Intrauterine Transfer of Mosaic Aneuploid Blastocysts [PDF]
Case Reports in Obstetrics and Gynecology, 2022 The long-term prognosis and genetic mechanism of pregnancy after intrauterine mosaic aneuploid blastocyst transfer remain unknown. We report the case of two babies after the aforementioned procedure and chromosomal analysis of their cord blood and ...
Yuki Ito +10 more
doaj +2 more sources
Discordant structural chromosomal aberrations in chorionic villi and amniotic fluid leading to a formation of an isochromosome 21: a case report [PDF]
Molecular Cytogenetics, 2021 Background Fetoplacental discrepancies occur in approximately 1–2% of analyzed prenatal cases. They are typically due to confined placental mosaicism, where an aberration is observed in the placental cells but not found in the fetal cells.
Eini Westenius +2 more
doaj +2 more sources
Microplastic abundance in placental chorionic villi detected by pyrolysis-gas chromatography/mass spectrometry in cases of spontaneous miscarriage during early pregnancyResearch in context [PDF]
EBioMedicineSummary: Background: There is widespread concern regarding the effect of microplastics (MPs) on human reproductive health. The accumulation of MPs and their potential effect on adverse pregnancy outcomes must be determined, particularly from the ...
Peixin Wang +6 more
doaj +2 more sources
Salmonella Typhi-Exposed Placentae: Chorionic Villi Histomorphology and Neonatal Birthweight [PDF]
DiseasesBackground: Salmonella infections impose a substantial global health burden, with an estimated 95.1 million cases occurring annually. Pregnant women exhibit a heightened vulnerability due to pregnancy-specific immune adaptations and dietary habits that ...
Patience B. Tetteh-Quarcoo +12 more
doaj +2 more sources
Protocol for Increasing the Sensitivity of MS-Based Protein Detection in Human Chorionic Villi [PDF]
Current Issues in Molecular Biology, 2022 Natalia Petushkova +2 more
exaly +2 more sources