Results 81 to 90 of about 7,094 (160)
ABSTRACT Objective We aim to increase knowledge on pregnancy and delivery risks in vascular Ehlers–Danlos Syndrome (vEDS). Our outcomes can contribute to establishing future guidelines for pregnancy and delivery management in women with vEDS. Design Retrospective multicentre cohort study.
Lisa M. van den Bersselaar +13 more
wiley +1 more source
A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng +14 more
wiley +1 more source
Prenatal exposure to organophosphorus flame retardants (OPFRs) has been linked with adverse effects on reproductive health, and new OPFRs are continually emerging. In this study, emerging OPFRs, such as bis(2-ethylhexyl) phenyl phosphate (BEHPP), triamyl
Linwan Li +3 more
doaj +1 more source
The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen +18 more
wiley +1 more source
Mosaic trisomy 5 in amniotic fluid in a live fetus with Ebstein anomaly and complete trisomy 5 in chorionic villus sampling. [PDF]
Andrade A +3 more
europepmc +1 more source
ABSTRACT Patients diagnosed with gestational trophoblastic diseases (GTD) can develop malignant gestational trophoblastic neoplasia (GTN). ß‐hCG monitoring is important in the early detection of GTN. The primary outcome of this study was to describe ß‐hCG monitoring completion rates and time from GTN diagnosis to chemotherapy commencement for patients ...
Harrison Odgers +2 more
wiley +1 more source
A retrospective study of 98 fetuses with congenital duodenal obstruction (CDO) revealed an overall genetic abnormality rate of 20.4%, with trisomy 21 being the predominant chromosomal anomaly. Comprehensive prenatal diagnostic testing is recommended for fetuses with suspected congenital duodenal obstruction, as the genetic findings exert substantial ...
Jianqin Lu +16 more
wiley +1 more source
Comparison of aneuploidy rate in spontaneous abortion chorionic villus between D6 and D5 thawed-frozen blastocyst transfer. [PDF]
Zhao W +5 more
europepmc +1 more source
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri +6 more
wiley +1 more source

