Results 131 to 140 of about 91,251 (315)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Carcinoma, choroid plexus

, 1997
Carcinoma, choroid ...

core  

Cerebrospinal fluid secretion by the choroid plexus

, 2013
The choroid plexus epithelium is a cuboidal cell monolayer, which produces the majority of the cerebrospinal fluid. The concerted action of a variety of integral membrane proteins mediates the transepithelial movement of solutes and water across the ...
Brown, Peter, Praetorius, Jeppe, Brown, Peter D., Damkier, Helle H.   +3 more
core   +1 more source

A Nationwide Central Diagnosis for Pediatric CNS Tumors in Japan: The JCCG Brain Tumor and Pathology Committees

Cancer Science, EarlyView.
In this report, we present the results of a nationwide initiative launched by the Japan Children's Cancer Group to provide integrated diagnoses for pediatric central nervous system (CNS) tumors, incorporating central pathological review and molecular profiling.
Yoshiko Nakano, Junko Hirato, Takako Yoshioka, Tetsuya Takimoto, Sumihito Nobusawa, Kaishi Satomi, Ran Tomomasa, Seiji Yamada, Taku Homma, Shoh Sasaki, Ayako Yamazaki, Maki Sakaguchi, Yasuhide Takeuchi, Nei Fukazawa, Kai Yamasaki, Kohei Fukuoka, Yui Shinohara Kimura, Yuki Nagayama, Yohei Inoue, Akira Miyahira, Ema Yoshioka, Asako Katsuma, Hayato Fukusumi, Tomoko Shofuda, Yuko Hibiya, Yuko Matsushita, Mai Honda Kitahara, Yuki Yomoda, Miho Kato, Michael D. Taylor, Yasuhito Arai, Tatsuhiro Shibata, Hiroaki Sakamoto, Keita Terashima, Yoshiki Arakawa, Toshihiro Kumabe, Ryo Nishikawa, Junichi Hara, Yonehiro Kanemura, Koichi Ichimura   +39 more
wiley   +1 more source

Water-filled vesicles of choroid plexus tumors

, 2019
ozmen, sevilay/0000-0002-1973-6101;Objective: Choroid plexus cysts are the most common neuroepithelial cysts. Methods: the authors describe 2 cases. the first case is a 1-year-old child presenting with hydrocephalus and cyst of the choroid plexus.
Aydın, Mehmet Dumlu, Sevilay Ozmen, AYDIN, Mehmet Dumlu, Özmen, Sevilay, Karaavcı, Nuh Çağri, Şahin, Hakan, Hakan Sahin, Ayhan Kanat, Mehmet Dumlu Aydin, Nuh Cagri Karaavci, Kanat, Ayhan, Karaavci, Nuh Cagri   +11 more
core   +1 more source

Aqueous Humour Cytokines as Predictors of Axial Elongation in High Myopia: A 2‐Year Longitudinal Cohort Study

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate the predictive value of aqueous humour cytokines for axial elongation. Methods This was a prospective longitudinal observational study. 72 high myopia patients (72 eyes) who received implantable collamer lens (ICL) implantation surgery with at least 2 years of follow‐up were included.
Lihui Meng, Yan Luo, Zhengming Shi, Youxin Chen, Zhikun Yang   +4 more
wiley   +1 more source

Choroid plexus blood flow: evidence for dopaminergic influence

, 2010
Choroid plexus blood flow was measured in adult female sheep using the radioactive microsphere technique. The response of choroid plexus, renal and cortical blood flow to the infusion of dopamine (11 sheep), haloperidol (7 sheep) and propranolol (6 sheep)
Brennan, Robert W., Ziedonis, Douglas M., Bryan, Robert M., Townsend, John B., Page, Robert B.   +4 more
core   +1 more source

Evidence for reduced choroid plexus volume in the aged brain

Fluids and Barriers of the CNS
Background The choroid plexus plays an important role in brain homeostasis, including the active secretion of cerebrospinal fluid. Its function and structure have been reported to be affected by normal ageing. However, existing measures of choroid plexus
R. Youh, C. Perera, C. Katsiva, I. F. Harrison, M. F. Lythgoe, D. K. Wright, S. Nizari, Jack A. Wells   +7 more
doaj   +1 more source

Abnormal Glycaemic Fluctuations Associated With Early Microvascular Changes in the Retina and Choroid of Nondiabetic Adults

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the association between continuous glucose monitoring (CGM)‐derived glycaemic variability indicators and early microvascular changes of the retina and choroid in nondiabetic individuals. Materials and Methods Community‐based individuals at high risk for type 2 diabetes (T2DM) underwent detailed assessments including oral ...
Yan Jiang, Liping Gu, Yuhang Ma, Yuan Qu, Hancong Wan, Kangjia Lv, Qian Zhu, Hao Zhou, Jian Sun, Fei Lu, Xiaowei Li, Yufei Wang, Jian Zhou, Kun Liu, Yufan Wang, Yinchen Shen   +15 more
wiley   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source