Results 121 to 130 of about 124,855 (302)
Research status and trends of Piezo1 and brain: A bibliometric analysis
Neuroprotection, EarlyView.This graphical abstract illustrates the workflow and key findings of the bibliometric analysis of Piezo1 in brain research. The primary results were visually centered on a brain graphic highlighting the Piezo1 channel, and three converging research hotspots were identified: neurovascular regulation, calcium signaling, and neuroinflammation.
Yu Liu +8 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa +7 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To investigate the additional clinical value of nuchal translucency (NT) measurement at the first‐trimester anomaly scan (FTAS) in a setting with first‐tier non‐invasive prenatal testing (NIPT). Method This nationwide prospective cohort study, part of the IMITAS study on FTAS implementation, included all pregnancies with increased NT
Eline E. R. Lust +15 more
wiley +1 more source
Moderate Diagnostic Yield of Exome Sequencing in Fetal Growth Restriction: Retrospective Insights
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To determine whether invasive genetic testing should be systematically proposed in cases of FGR. Methods Descriptive retrospective study of 159 FGR cases (defined by an estimated fetal growth < 3rd percentile, regardless of Doppler findings) managed at the Toulouse Fetal Medicine Center (TFMC) during 2022–2023.
Maud Langeois +5 more
wiley +1 more source
Diagnostic Yield of Post‐Mortem Fetal Micro‐CT for Central Nervous System Abnormalities
Prenatal Diagnosis, EarlyView.ABSTRACT Objectives This study demonstrates the central nervous system (CNS) abnormalities detected using fetal post‐mortem micro‐focus computed tomography (Micro‐CT), independent of whether the abnormality contributed to the main diagnosis or cause of death.
Ian C. Simcock +5 more
wiley +1 more source
Current Insight into Human Ornithine Aminotransferase: A Review
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Human ornithine aminotransferase (hOAT) is a mitochondrial matrix pyridoxal‐5′‐phosphate enzyme (PLP) that catalyzes the reversible transfer of the δ‐amino group of L‐ornithine (L‐Orn) to α‐ketoglutarate (α‐KG) yielding glutamate‐5‐semialdehyde (GSA) and glutamate. GSA is prone to cyclize to Δ1‐pyrroline‐5‐carboxylate.
Fulvio Floriani +2 more
wiley +1 more source
Fluids and Barriers of the CNSThe Hindbrain Choroid Plexus is a complex, cerebrospinal fluid-secreting tissue that projects into the 4th vertebrate brain ventricle. Despite its irreplaceability in the development and homeostasis of the entire central nervous system, the research of ...
Viktória Parobková +8 more
doaj +1 more source
Structure and optics of the anterior segment of the cetacean eye : a thesis presented in fulfilment of the requirements for the degree of Master of Philosophy at Massey University [PDF]
, 1999 The anterior segment of the mammalian eye is concerned with the function and maintenance of its optical components, the most important of these being the maintenance of transparency and stable intraocular pressure.
Mellor, Lynda
core
Small Methods, EarlyView.This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto +12 more
wiley +1 more source