Results 161 to 170 of about 124,855 (302)

Variability in intracellular localization of D‐amino acid oxidase in choroid plexus epithelial cells

open access: yesThe FEBS Journal, EarlyView.
D‐amino acid oxidase (DAO) in choroid plexus epithelial cells (CPECs) shows vesicle‐like localization by histological and super‐resolution analyses. DAO colocalizes with peroxisomal, Golgi, endosomal, lysosomal, autophagosomal, and exosomal markers, indicating diverse subcellular distribution. This suggests DAO is transported within CPECs to metabolize
Koji Ono   +3 more
wiley   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

Anatomy of spinal CSF loss in the American alligator (Alligator mississippiensis)

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 575-584, April 2025.
India ink introduced into the cranial cerebrospinal fluid (CSF) compartment of Alligator diffuses along the spinal cord and exits the spinal compartment using perineural flow, resulting in a prominent “ink cuff” forming at the base of the spinal nerve. In Alligator, the region of the ink cuff is drained by a small lymphatic vessel.
Hadyn DeLeeuw   +5 more
wiley   +1 more source

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

open access: yesJournal of Anatomy, EarlyView.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou   +6 more
wiley   +1 more source

Ocular Transmission of Red and Violet Light: Insights into Light-Based Myopia Therapies. [PDF]

open access: yesTransl Vis Sci Technol
Priscilla JJ   +4 more
europepmc   +1 more source

Contribution to the theory of photopic vision: Retinal phenomena [PDF]

open access: yes
Principles of thermodynamics are applied to the study of the ultramicroscopic anatomy of the inner eye. Concepts introduced and discussed include: the retina as a three-dimensional sensor, light signals as coherent beams in relation to the dimensions of ...
Calvet, H.
core   +1 more source

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