Results 201 to 210 of about 78,813 (321)

Enlarged choroid plexus is linked with poorer physical function in rural older adults: a population-based study. [PDF]

open access: yesFluids Barriers CNS
Xie Q   +13 more
europepmc   +1 more source

The Natural Course of Bosch‐Boonstra‐Schaaf Optic Atrophy Syndrome

open access: yesClinical Genetics, EarlyView.
Here, we present data on genetic variants and phenotype development of 47 individuals with Bosch‐Boonstra‐Schaaf optic atrophy syndrome, a rare neurodevelopmental disorder, highlighting the fact that the disease does not appear to be fundamentally progressive.
Ilia Valentin   +4 more
wiley   +1 more source

Klotho Regulates Club Cell Senescence and Differentiation in Chronic Obstructive Pulmonary Disease

open access: yesCell Proliferation, EarlyView.
We speculated lack of Klotho (KL) would aggravate club cell senescence, which contributes to COPD inflammation. In this study, we collected chronic obstructive pulmonary disease (COPD) lung tissue using single‐cell RNA sequencing (scRNA‐seq), revealing club cell heterogeneity and cellular senescence in COPD.
Min Li   +5 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

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