Results 281 to 290 of about 78,813 (321)

Correlation of retinal fluid and photoreceptor and RPE loss in neovascular AMD by automated quantification, a real‐world FRB! analysis

open access: yesActa Ophthalmologica, Volume 103, Issue 3, Page 295-303, May 2025.
Abstract Purpose To quantify ellipsoid zone (EZ) loss during anti‐VEGF therapy for neovascular age‐related macular degeneration (nAMD) and correlate these findings with nAMD disease activity using artificial intelligence‐based algorithms. Methods Spectral domain optical coherence tomography (Spectralis, Heidelberg Engineering) images from nAMD ...
Virginia Mares   +7 more
wiley   +1 more source

Effect of 0.025% atropine on ocular biometry changes during accommodation

open access: yesOphthalmic and Physiological Optics, Volume 45, Issue 3, Page 865-876, May 2025.
Abstract Purpose Low concentration atropine is an effective treatment to slow myopia progression and axial elongation and also reduces accommodation. On‐axis ocular dimensions of the eye change during accommodation; hence, this study aimed to quantify the effect of 0.025% atropine eye drops on accommodation‐induced changes in ocular biometry.
Rohan P. J. Hughes   +4 more
wiley   +1 more source

Intensity-Based Assessment of Hippocampal Segmentation Algorithms Using Paired Precontrast and Postcontrast MRI. [PDF]

open access: yesBioengineering (Basel)
Cramer J   +8 more
europepmc   +1 more source

Single‐Cell Transcriptomes of Immune Cells from Multiple Compartments Redefine the Ontology of Myeloid Subtypes Post‐Stroke

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
Using single‐cell sequencing in a murine stroke model (p‐MCAO), three stroke‐specific subpopulations are identified: disease inflammatory macrophage (DIM), disease‐associated microglia (DAM), and CD14+ neutrophils (Neut_Cd14). Detailed analyses reveal that Neut_Cd14 and DIM subtypes are skull‐derived, whereas DAM likely originates from homeostatic ...
Mo Yang   +9 more
wiley   +1 more source

A Serum Resistant Polymer with Exceptional Endosomal Escape and mRNA Delivery Efficacy for CRISPR Gene Therapy

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
A fluoropolymer, FD17, identified in a polymer library, exhibits exceptional serum stability and endosomal escape, enabling efficient mRNA delivery. FD17 facilitates the intracellular delivery of mRNAs encoding CRE, Cas9, and hyCBE for genome editing.
Jia Lv   +8 more
wiley   +1 more source

Investigation of choroid plexus variability in schizophrenia-spectrum disorders-insights from a multimodal study. [PDF]

open access: yesSchizophrenia (Heidelb)
Yakimov V   +22 more
europepmc   +1 more source

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