Results 41 to 50 of about 14,157 (210)

Current Insight into Human Ornithine Aminotransferase: A Review

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Human ornithine aminotransferase (hOAT) is a mitochondrial matrix pyridoxal‐5′‐phosphate enzyme (PLP) that catalyzes the reversible transfer of the δ‐amino group of L‐ornithine (L‐Orn) to α‐ketoglutarate (α‐KG) yielding glutamate‐5‐semialdehyde (GSA) and glutamate. GSA is prone to cyclize to Δ1‐pyrroline‐5‐carboxylate.
Fulvio Floriani   +2 more
wiley   +1 more source

A partial gene deletion of SLC45A2 causes oculocutaneous albinism in Doberman pinscher dogs. [PDF]

open access: yesPLoS ONE, 2014
The first white Doberman pinscher (WDP) dog was registered by the American Kennel Club in 1976. The novelty of the white coat color resulted in extensive line breeding of this dog and her offspring.
Paige A Winkler   +6 more
doaj   +1 more source

Clinical reasoning in feline non‐ambulatory tetraparesis or tetraplegia: Which combination of clinical information is useful?

open access: yesVeterinary Record, EarlyView.
Abstract Background Non‐ambulatory tetraparesis or tetraplegia in cats may constitute a diagnostic challenge for general practitioners. Therefore, this study aimed to evaluate if clinical variables from signalment, history, clinical examination and basic ancillary tests are associated with underlying diagnoses in cats with non‐ambulatory tetraparesis ...
Guido Bertoldi, Steven De Decker
wiley   +1 more source

Visual impairment due to bilateral multifocal choroidal metastasis of parotid adenocarcinoma: a case report.

open access: yesFrontiers in Oncology, 2014
BackgroundOrbital metastases are an uncommon finding, being present in just 9% deceased patients with metastatic cancer. Only a quarter of patients with choroidal metastases have bilateral disease.
Gerard eWalls   +2 more
doaj   +1 more source

Intraocular Medulloepitheliomae (Clinical Case Series)

open access: yesOftalʹmologiâ, 2020
Purpose. Retrospective analysis of clinical, instrumental, cytological and pathological features of intraocular medulloepithelioma based on our own experience in the period from 2005 to 2018. Patients and Methods.
S. V. Saakyan   +7 more
doaj   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

open access: yesVIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf   +5 more
wiley   +1 more source

Infection control in the brain and the eye

open access: yesActa Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester   +2 more
wiley   +1 more source

Foramen of Monro choroid plexus papilloma: An extremely rare location managed by endoscopic resection

open access: yesRadiology Case Reports
Choroid plexus papillomas are rare brain neoplasms, primarily observed in children, and typically manifest with symptoms indicative of heightened intracranial pressure and cerebral irritation. In addition, the tumor's localization varies with the patient'
Mahmoud Abdallat, MD   +7 more
doaj   +1 more source

Non-neoplastic situations simulating choroidal melanoma and other intraocular neoplasms

open access: yesGüncel Retina Dergisi (Current Retina Journal), 2023
Multiple non-neoplastic situations might simulate intraocular neoplasms. As in every case detailed anamnesis, history, self and family background are important in discrimination. Even thoguh the clinical signs might be confusing multimodal imaging is mandatory for differential diagnosis.
Melis PALAMAR, Suzan GÜVEN YILMAZ
openaire   +1 more source

Age distribution and characteristics of choroidal nevi in 35 559 individuals: A nationwide study using optometry fundus photography

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To examine the age distribution and characteristics of choroidal nevi in a large nationwide sample. Methods We included all individuals who underwent fundus photography in a nationwide chain of optometry stores during a 5‐week period in 2023.
Carsten Faber   +3 more
wiley   +1 more source

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