Results 71 to 80 of about 4,884 (236)

Nonsteroidal Anti‐Inflammatory Drugs as Modulators of Cation Channels: Fenamates Repurposing in Channelopathies

open access: yesChemMedChem, Volume 20, Issue 20, October 15, 2025.
Beyond their established role as nonsteroidal anti‐inflammatory drugs (NSAIDs), fenamates (niflumic, flufenamic, mefenamic, meclofenamic, and tolfenamic acids) have recently been identified as modulators of cationic ion channels. This review highlights their differential effects on ion channel activity and explores their potential for repurposing in ...
Paola Laghetti   +4 more
wiley   +1 more source

Human Polyomavirus BK Genome Analysis in BKPyV Induced Rodent Cell Lines

open access: yesMicrobiologyOpen, Volume 14, Issue 5, October 2025.
In this study, we analyzed the BK polyomavirus (BKPyV) genome derived from three rodent cell lines established from BKPyV induced tumors. BKPyV derived one cell line had a large deletion. The noncoding control region (NCCR) of BKPyV derived from these cell lines had the same structure as viruses induced tumors.
Setsuko Shioda   +6 more
wiley   +1 more source

Síndrome de Aicardi en un neonato: reporte de un caso [PDF]

open access: yes, 2007
Se informa el caso de un recién nacido de sexo femenino que padecía microftalmia derecha, microcórnea, coloboma del iris, crisis convulsivas, agenesia de cuerpo calloso, hidrocefalia no activa y quiste interhemisférico supratentorial.
Cervantes Flores, Ricardo   +5 more
core  

Manganese Neurotoxicity and Familial Disorders of Manganese Transport

open access: yesAnnals of the Child Neurology Society, Volume 3, Issue 3, Page 135-144, September 2025.
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley   +1 more source

Magnetic Resonance Imaging of Unusual Neoplasms Related to Foramen of Luschka: A Review for Differential Diagnosis

open access: yesIndian Journal of Radiology and Imaging, 2022
There are many types of neoplasms in or around the foramen of Luschka (FL), and definitive diagnosis in some cases requires knowledge of imaging findings.
Mustafa Kemal Demir   +4 more
doaj   +1 more source

Pitfalls and Artifacts in Nuclear Imaging Studies [PDF]

open access: yes, 1975
In interpreting scintillation images, one often is confronted with a variety of deviations from the typically normal study that need not represent definite pathology.
Freeman, Leonard M.
core   +1 more source

The TP53 tumor suppressor gene: From molecular biology to clinical investigations

open access: yesJournal of Internal Medicine, Volume 298, Issue 2, Page 78-96, August 2025.
Abstract Extensively studied over the past four decades, the TP53 gene has emerged as a pivotal watchman in cellular defense and a key factor in cancer biology. TP53 is the most frequently mutated gene in human malignancies, 50% of which carry alterations to it.
Panagiotis Baliakas, Thierry Soussi
wiley   +1 more source

Congenital Intracranial Tumors: Prenatal Diagnosis by Fetal Magnetic Resonance Imaging

open access: yesiRADIOLOGY, Volume 3, Issue 3, Page 203-208, June 2025.
Fetal intracranial tumors are rare, comprising 0.5%–1.9% of all childhood tumors, with their true incidence potentially underestimated. This review highlights the role of fetal MRI, particularly with advanced sequences, in diagnosing common fetal brain tumors such as teratomas, astrocytomas, and choroid plexus papillomas, often presenting unique ...
Jing‐Ya Ren   +3 more
wiley   +1 more source

A Case of Choroid Plexus Papilloma with Rare Location Presenting with Impaired Consciousness

open access: yesİstanbul Medical Journal, 2019
Intraventricular papillary neoplasms originating from the choroid plexus epithelium are called choroid plexus tumors (CPT). In pediatric patients.
Nurcan Ünal   +6 more
doaj   +1 more source

Imaging Assessment of the Pituitary Gland and Long‐Term Endocrinological Abnormalities in Pediatric Brain Cancer Survivors

open access: yesJournal of Magnetic Resonance Imaging, Volume 61, Issue 6, Page 2516-2522, June 2025.
Background Pediatric brain cancer survivors often experience hypothalamic–pituitary dysfunction due to cranial irradiation and chemotherapy. While hormone deficiencies have been studied, the changes in pituitary size and shape on long‐term MRI and their relationship to endocrine dysfunction remain under‐explored.
Feras Qawasmi   +8 more
wiley   +1 more source

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