Results 51 to 60 of about 7,681 (179)

Delivery Systems for Therapeutic Genome Editing: Challenges, Innovations, and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Schematic illustration of four emerging CRISPR–Cas delivery platforms defined by distinct design principles and structural features: virus‐mimicking nanosystems (e.g., VLPs), cell‐derived extracellular vesicles, cell‐penetrating peptides, and stimuli‐responsive scaffolds. These platforms enable spatiotemporally controlled delivery of RNPs, mRNA, or DNA
Meijia Yang, Yiqiong Song, Ziyang Wang, Ke Chao, Lifeng Li, Xu Zhang, Xiaoran Duan, Chenglong Yu, Ruyue Xue, Jie Zhao   +9 more
wiley   +1 more source

Pseudo-pigmented choroidal schwannoma with extraocular extension in an elderly patient

American Journal of Ophthalmology Case Reports
Purpose: To describe a rare case of clinically pigmented choroidal schwannoma with extraocular extension in an elderly patient. Observations: We report a case of a 79-year-old Black male who presented with a clinically pigmented, juxtapapillary choroidal
Arnulfo Garza Reyes, Chad Y. Lewis, Chau Pham, H. Culver Boldt, Lola P. Lozano, Nasreen A. Syed, Elaine M. Binkley   +6 more
doaj   +1 more source

P132

EJC Supplements, 2015
To research the characteristics of the inflammation immune disorders and cell destruction at the local level in the lacrimal and intraocular liquids in patients with choroidal melanoma.
M. Chernyavskaya, V. Chernych, A. Efremov, V. Atamanov   +3 more
doaj   +1 more source

Meeting Report From the 2025 Cure Ocular Melanoma (CURE OM) Global Science Meeting, Amsterdam, the Netherlands, October 2025

Pigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
ABSTRACT The 2025 Cure Ocular Melanoma (CURE OM) Global Science Meeting took place in Amsterdam, The Netherlands on October 25th, 2025. Several promising drug candidates are in development; however, there is still an urgent need for better prevention, detection, and treatment of uveal melanoma.
Andrew E. Aplin, Katherina Alsina, Allison S. Betof, Joseph Birkett, Marcus O. Butler, George Cole Jr., Rizwan Haq, Florian A. Karreth, Vinit B. Mahajan, Rahul Marpadga, Prithvi Mruthyunjaya, Paul Nathan, Jonas A. Nilsson, Gary Palmer, Joseph J. Sacco, Takami Sato, Sarah Stanhope, Pang‐ning Teng, Kyleigh LiPira   +18 more
wiley   +1 more source

Impact of Multigene Panel Testing in High‐Risk Uveal Melanoma Patients

Pigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
National Comprehensive Cancer Network (NCCN) provides clear criteria for genetic testing among uveal melanoma (UM) patients. However, the efficacy of these guidelines to detect variants in actionable cancer genes has not been evaluated recently. Additionally, comprehensive panel testing has not been broadly standardized across genetic counseling ...
Lindsey Byrne, Isabella Gray, Kaylee Ramsey, Joseph McElroy, Emma Schreiner, Jenna Wolfe, Olivia B. Taylor, Frederick Davidorf, Colleen M. Cebulla, Mohamed H. Abdel‐Rahman   +9 more
wiley   +1 more source

Complete Regression of bilateral Choroidal Metastases secondary to a Cutaneous Melanoma under Immunotherapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Yenny Angela, Alena Riesmeier, Ralf Gutzmer, Miltiadis Fiorentzis, Nikolaos E. Bechrakis, Carsten Framme, Ekaterina Sokolenko   +6 more
wiley   +1 more source

Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain

Advanced Materials, Volume 38, Issue 32, 8 June 2026.
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha, Bilguun Nurzed, Mostafa Berangi, Andre Kuehne, Helmar Waiczies, Igor Fabian Tellez Ceja, Xiang Hu, Thomas Gladytz, Lisa Krenz, Dave Huebler, Beate Endemann, Claudia Brockmann, Ebba Beller, Oliver Stachs, Thoralf Niendorf   +14 more
wiley   +1 more source

A 51‐year‐old female presenting with headache and vision loss

Headache: The Journal of Head and Face Pain, EarlyView.
Laurel Ovrom, Zachary Pardieck, Randy Christopher Bowen, Neena R. Cherayil   +3 more
wiley   +1 more source

Evolutionary Origin of Ocular Melanoma: Associations With rs12913832 G Allele Frequency and Latitude

Cancer Medicine, Volume 15, Issue 6, June 2026.
The rs12913832 derived (G) allele frequency (blue‐eye allele) was a markedly stronger predictor of ocular melanoma incidence than geographic latitude, with approximately 92% of the latitude effect mediated through allele frequency. These findings indicate that pigmentation‐related genetic variation contributes substantially to global differences in ...
Hans Witzenhausen, Hildur Helgadottir, Veronica Höiom, Roger Olofsson Bagge, Gustav Stålhammar   +4 more
wiley   +1 more source

Factors associated with time until metastatic spread in patients with primary uveal melanoma: A retrospective analysis.

PLoS ONE
PurposeTo characterize patients with choroidal or ciliary body (CB) melanoma in order to identify factors associated with time until metastasis and further perform a detailed characterization of the factors identified.MethodsA mixed model approach was ...
Reinhard Told, Adrian Reumueller, Judith Kreminger, Stefan Sacu, Roman Dunavoelgyi   +4 more
doaj   +1 more source