Repeatability of SpotChecks contrast sensitivity test in macular disease
ABSTRACT Purpose SpotChecks is an accessible contrast sensitivity test with good repeatability in healthy adults. This study compared its intra‐visit repeatability with the near Pelli–Robson test in adults with macular disease. Methods One eye from 29 adults with macular disease (mean age 71 ± 13 years) underwent high‐contrast logMAR acuity and two ...
Katlyn B. Sprague +4 more
wiley +1 more source
Comprehensive review of angioid streaks
Angioid streaks are irregular breaks in the brittle Bruch’s membrane and commonly present as pigmented linear lines radiating from the optic disc. They may be associated with systemic disease in up to 50% of the patients.
Sindhuja Kandasamy +7 more
doaj +1 more source
Intravitreal Delivery of Cationic DMP Micelles Suppresses Choroidal Neovascularization
MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Yingying Chen +5 more
wiley +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
Species differences in choroidal vasodilative innervation: evidence for specific intrinsic nitrergic and VIP-positive neurons in the human eye [PDF]
The presence of an intrinsic nerve cell plexus that is specifically localized in human eyes in the temporal-central portion of the choroid indicates a functional significance of the nitrergic choroidal innervation for the ...
Tamm, Ernst R. +3 more
core +1 more source
Foundation Models in Diagnosis of Ophthalmic Diseases: Construction and Application
ABSTRACT Artificial intelligence holds promise for addressing the uneven distribution of medical resources across different regions. Compared with convolutional neural network models, foundation models offer significant advantages: on one hand, their pre‐training does not rely on massive labeled data; on the other hand, they possess the capability to ...
Xiaolu Huang +7 more
wiley +1 more source
Genetic Epidemiology of Age-Related Macular Degeneration (AMD): The Role of the Complement Component 2 (C2) and Complement Factor B (CFB) Genes in Determining AMD Subphenotypes [PDF]
Age-related macular degeneration (AMD) is the most common cause of irreversible blindness in people over the age of 50 in the developed world. Inflammation has a central role in the pathobiology of AMD; complement pathway dysfunction is thought to induce
Longville, Brooke Allison Cattell
core
Objective: To study tumor characteristics of choroidal osteoma by swept source optical coherence tomography. Methods: A retrospective case series done at tertiary referral center in northern India.
Shorya Vardhan Azad +9 more
doaj +1 more source
Large choroidal melanoma presenting as neovascular glaucoma
Choroidal melanoma is a relatively rare tumour with a poor prognosis, though it is the most common primary malignancy of the eye among adults. Choroidal melanoma has been reported to present as acute angle closure glaucoma, secondary glaucoma, chronic ...
Shrestha, V +4 more
core +1 more source
Intracameral Injection of Bevacizumab for the Treatment of Neovascular Glaucoma [PDF]
Purpose: To assess the duration of the effect of intracameral bevacizumab in patients presenting with rubeosis iridis and neovascular glaucoma (NVG). Methods: Retrospective analysis of 24 consecutive eyes of 24 patients with decompensated NVG (> 21 mm Hg)
Haritoglou, Christos +7 more
core +1 more source

