Results 71 to 80 of about 63,614 (216)

Microglial Labeling in Mouse Spinal Cord Injury: A Review of Timing, Efficacy, and Specificity

Glia, Volume 74, Issue 12, December 2026.
The transcriptional profile of microglia is significantly altered after spinal cord injury (SCI). When choosing a marker to label microglia after SCI, it is important to consider its specificity for microglia and its stability of expression. ABSTRACT Traumatic spinal cord injury (SCI) is a complex and disabling condition with no curative therapy ...
Ruth Colbert, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

MULTIMODAL IMAGING AND TREATMENT OF SYPHILITIC CHOROIDAL NEOVASCULARIZATION

, 2022
To report a rare case of choroidal neovascularization (CNV) developed 2 years after successful treatment of ocular syphilis, identified by optical coherence tomography ...
Giuseppe Querques, Miserocchi, Elisabetta, Cicinelli, Maria Vittoria, Chiara Giuffrè, Giulio Modorati, Elisabetta Miserocchi, Maria Vittoria Cicinelli, Querques, Giuseppe, Modorati, Giulio, Bandello, Francesco, Marchese, Alessandro, Francesco Bandello, Alessandro Marchese, Giuffrè, Chiara   +13 more
core   +1 more source

The impacts of high refractive errors on self‐reported visual function and visual concern

Acta Ophthalmologica, Volume 104, Issue 7, Page 780-788, November 2026.
Abstract Purpose To examine the association between refractive errors and self‐reported visual function and visual concern, considering self‐perceived present eyesight, concerns about vision, accomplishing less and limitations in daily activities in an eye‐healthy cohort.
Jens Riis Møller, Arevak Saruhanian, Jens Rovelt, Josefine Freiberg, Marcel Reimann, Jeppe Nygård Samuelsen, Christina Eckmann‐Hansen, Miriam Kolko, Nina Jacobsen, FOREVER Consortium   +9 more
wiley   +1 more source

Reduction of choroidal neovascularization via cleavable VEGF antibodies conjugated to exosomes derived from regulatory T cells

, 2021
Intravitreally injected exosomes derived from regulatory T cells and conjugated with an antibody for vascular endothelial growth factor via a cleavable linker markedly suppress ocular neovascularization in mice and non-human primates.
Yu, Di, Tian, Ying, Li, Feng, Wei, Wei, Qiu, Yefeng, Tao, Yong, Wang, Shuang, Zhao, Jiawei, Zhang, Fan, Pan, Chao, Yefeng Qiu, Jiawei Zhao, Fan Zhang, Feng Li, Ying Tian, Shuang Wang, Chao Pan, Di Yu, Wei Wei, Yong Tao   +19 more
core   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9809-9818, November 2026.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Treatment of Choroidal Neovascularization Associated With Best’s Disease in Children

, 2009
The development of secondary choroidal neovascularization in Best's disease is rare in the pediatric population. A retrospective review of pediatric patients with choroidal neovascularization secondary to Best's disease was performed.
Vanderveldt, Stephanie, Audina M. Berrocal, Elias C. Mavrofrides, Stephanie Vanderveldt, Murray, Timothy G, Gregori, Ninel, Mavrofrides, Elias C, Berrocal, Audina M, Rich, Ryan, Timothy G. Murray, Ryan Rich, Ninel Gregori   +11 more
core   +1 more source

Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization Secondary to Endogenous Endophthalmitis

Kaohsiung Journal of Medical Sciences, 2009
Choroidal neovascularization is a major cause of visual loss in age-related macular degeneration. It is also a potential vision-threatening complication of pathologic myopia, uveitis, traumatic choroidal rupture and, rarely, endophthalmitis.
Shwu-Jiuan Sheu
doaj   +1 more source

From Molecular Targets to Advanced Delivery Systems: Aptamers for Precision Ocular Therapeutics

Advanced Therapeutics, Volume 9, Issue 10, October 2026.
Aptamer‐based strategies are revolutionizing ocular disease management through highly specific molecular recognition of disease specific molecular targets. This review systematically integrates therapeutic aptamer sequences, diagnostic aptasensor platforms, and targeted delivery strategies, highlighting design principles, ocular bioavailability ...
Minal Thacker, Ka‐Ying Wong, Liping Zhou, Man‐Sau Wong, Juewen Liu   +4 more
wiley   +1 more source

Choroidal neovascular membrane.

Indian journal of ophthalmology, 1998
Choroidal neovascular membrane in the macular area is one of the leading causes of severe visual loss. Usually a manifestation in elderly population, it is often associated with age-related macular degeneration. The current mainstay of management is early diagnosis, usually by fundus examination, aided by angiography and photocoagulation in selected ...
Bhatt Nitul, Diamond James, Jalali Subhadra, Das Taraprasad   +3 more
openaire   +2 more sources

Spontaneous transition of focal choroidal excavation from a nonconforming to a conforming form: Unusual clinical presentation

Indian Journal of Ophthalmology. Case Reports
Focal choroidal excavation (FCE) represents a macular choroidal concavity. It is categorized as conforming and nonconforming, and may be associated with complications such as choroidal neovascularization.
Karol Quintero Lizcano, Juan Manuel Correa Alvarez, Sarita Restrepo Velásquez, Mauricio Arango Hurtado   +3 more
doaj   +1 more source