Results 81 to 90 of about 35,691 (227)

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age‐Related Macular Degeneration

Aging Cell, Volume 25, Issue 5, May 2026.
A Bruchs membrane (BrM) mimic based on aged decellularized BrM was developed and differentially expressed proteins in aged dECM‐BrM that may provide specific biochemical cues fundamental to model AMD in vitro were identified. RPE culture on aged dECM‐BrM developed certain AMD‐like features including reduced TEER and expression of drusen components ...
Blanca Molins, Mercedes Soledad Nabaes Jodar, Eliandre de Oliveira, Josep Maria Estanyol, Esther Peña, Jaione Bezunartea, María Hernández, Marc Figueras‐Roca, Alfredo Adan   +8 more
wiley   +1 more source

Retinal pigment epithelial tears after intravitreal bevacizumab injection for exudative age-related macular degeneration. [PDF]

, 2008
PURPOSE: To determine the incidence of and the risk factors for the development of retinal pigment epithelial (RPE) tears after intravitreal bevacizumab (Avastin) injection for the treatment of exudative age-related macular degeneration (AMD). METHODS: A
Brod, Roy, Fischer, David, Garg, Sunir, Kim, David, Lane, R Gary, Maguire, Joseph   +5 more
core   +2 more sources

Neovascular age‐related macular degeneration without drusen

Acta Ophthalmologica, Volume 104, Issue 3, Page e300-e311, May 2026.
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks, Elon H. C. van Dijk, Husein Ghalayini, Somayeh Bazdar, WeiFeng Yu, Suzanne Yzer, José P. Martinez Ciriano, Reinier O. Schlingemann, Roselie M. H. Diederen, Camiel J. F. Boon   +9 more
wiley   +1 more source

Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization Secondary to Endogenous Endophthalmitis

Kaohsiung Journal of Medical Sciences, 2009
Choroidal neovascularization is a major cause of visual loss in age-related macular degeneration. It is also a potential vision-threatening complication of pathologic myopia, uveitis, traumatic choroidal rupture and, rarely, endophthalmitis.
Shwu-Jiuan Sheu
doaj   +1 more source

Evaluation of 10 AMD Associated Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes. [PDF]

PLoS ONE, 2016
Choroidal neovascularization (CNV) commonly occurs in age related macular degeneration and pathological myopia patients. In this study we conducted a case-control prospective study including 431 participants.
Alvaro Velazquez-Villoria, Sergio Recalde, Jaouad Anter, Jaione Bezunartea, Maria Hernandez-Sanchez, Laura García-García, Elena Alonso, Jose María Ruiz-Moreno, Javier Araiz-Iribarren, Patricia Fernandez-Robredo, Alfredo García-Layana   +10 more
doaj   +1 more source

Traitement des membranes néovasculaires myopiques par ranibizumab : résultats à long terme. [PDF]

, 2014
Background: To report our functional results of efficacy of intravitreal ranibizumab (IVR) for submacular choroidal neovessels (CNV) in high myopia, and to compare the role of optical coherence tomography (OCT), fluorescein angiography (FA) and visual ...
LADAIQUE, M.
core  

Vascular Response to Sildenafil Citrate in Aging and Age-Related Macular Degeneration. [PDF]

, 2019
Age-related macular degeneration (AMD) - the leading cause of vision loss in the elderly - share many risks factors as atherosclerosis, which exhibits loss of vascular compliance resulting from aging and oxidative stress.
Agrawal, Rupesh, Cheung, Chui Ming Gemmy, Cunefare, David, Farsiu, Sina, Khandelwal, Neha, Migacz, Justin, Tran, Steven, Vuong, Vivian S, Yiu, Glenn   +8 more
core   +2 more sources

Pregnancy as a risk factor for central serous chorioretinopathy: A systematic review and meta‐analysis

Acta Ophthalmologica, Volume 104, Issue 3, Page 259-266, May 2026.
Abstract Purpose Pregnancy induces significant changes in the body, including increased peripheral and choroidal blood perfusion and an increased systemic corticosteroid level. Here, we systematically reviewed the evidence on pregnancy as a risk factor for developing central serous chorioretinopathy (CSC) and conducted a meta‐analysis to obtain a ...
Nathalie Skovgaard Eriksen, Zainab Fakhril‐din, Riccardo Fasana, Rodrigo Anguita, Elon H. C. van Dijk, Lorenzo Ferro Desideri, Jakob Grauslund, Michael Stormly Hansen, Oliver Niels Klefter, Armin Motaabbed, Line Petersen, Prithvi Ramtohul, Mehmet Cem Sabaner, Osman Savran, Miklos Schneider, Yousif Subhi   +15 more
wiley   +1 more source

Multiple choroidal osteomas in a boy – a rare presentation: a case report

Journal of Medical Case Reports, 2019
Background Choroidal osteoma is rare clinical entity of unknown etiology, characterized by formation of mature cancellous bone within the choroid. It typically affects young females, with no racial predilection.
Arup Deuri, Deepanjan Ghosh, Jayant Ekka, Vijaya Agarwalla   +3 more
doaj   +1 more source