Results 1 to 10 of about 250,265 (247)

Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling

open access: yesEBioMedicine, 2015
Retinal neovascularization is the most common cause of moderate to severe vision loss in all age groups. Despite the use of anti-VEGFA therapies, this complication continues to cause blindness, suggesting a role for additional molecules in retinal ...
Raj Kumar   +2 more
exaly   +4 more sources

Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease

open access: yesCase Reports in Ophthalmological Medicine, 2021
We report the rescue effect of intravitreal aflibercept injections on retinal neovascularization and macular edema due to Eales disease. Case 1 was a 36-year-old female. Intravitreal aflibercept was administered as rescue therapy after persistent retinal
Ning-Yi Hsia   +6 more
doaj   +2 more sources

Ocular Syphilis with Retinal and Disc Neovascularization Treated with Bevacizumab: A Case Report

open access: yesCase Reports in Ophthalmology, 2023
We report the findings observed in a young woman with ocular syphilis complicated with retinal and disc neovascularization successfully treated with intravitreal bevacizumab.
Lucia Comastri   +4 more
doaj   +2 more sources

Targeting Neuroinflammation in Neovascular Retinal Diseases [PDF]

open access: yesFrontiers in Pharmacology, 2020
Retinal blood vessels provide the necessary energy, nutrients and oxygen in order to support visual function and remove harmful particles from blood, thus acting to protect neuronal cells.
Tianxi Wang   +2 more
doaj   +3 more sources

Sea-fan retinal neovascularization associated with rickettsial retinitis: a case report [PDF]

open access: yesBMC Ophthalmology
Background Rickettsial disease has been commonly associated with retinitis, retinal vasculitis, and optic nerve involvement, but the development of retinal neovascularization has been very rarely reported.
Nesrine Abroug   +6 more
doaj   +2 more sources

Retinal neovascularization in the setting of -mutation positive essential thrombocythemia [PDF]

open access: yesSAGE Open Medical Case Reports, 2023
Patients with Calreticulin ( CALR ) mutation positive essential thrombocythemia are often thought of as having a “low-risk” of thrombotic complications.
Stanton P Heydinger   +2 more
doaj   +2 more sources

Methyltransferase-like 14 suppresses the retinal neovascularization by reducing HIF-1α in proliferative retinopathy [PDF]

open access: yesEuropean Journal of Medical Research
Background Proliferative retinopathy (PR), a leading cause of visual impairment, is characterized by pathological retinal neovascularization.
Jitian Guan   +7 more
doaj   +2 more sources

CM082 suppresses hypoxia-induced retinal neovascularization in larval zebrafish [PDF]

open access: yesFrontiers in Pharmacology
Retinal neovascularization is a common feature of several ocular neovascular diseases, which are the leading cause of blindness in the world. Current treatments are administered through invasive intravitreal injections, leading to poor patient compliance,
Jun-long Zhang   +4 more
doaj   +2 more sources

Peripapillary retinal neovascularization and vitreous hemorrhage secondary to peripapillary pachychoroid syndrome [PDF]

open access: yesAmerican Journal of Ophthalmology Case Reports
Purpose: To report a case of peripapillary pachychoroid syndrome (PPS) complicated with peripapillary retinal neovascularization causing vitreous hemorrhage.
Imène Zhioua Braham   +4 more
doaj   +2 more sources

Calcitriol Is a Potent Inhibitor of Retinal Neovascularization

open access: yesInvestigative Ophthalmology and Visual Science, 2007
Vitamin D compounds inhibit the growth of a variety of tumors in preclinical and clinical studies. Among the mechanisms suggested for this inhibition is antiangiogenesis. Retinal angiogenesis is the basis for vision loss in several major blinding diseases.
Christine M Sorenson   +2 more
exaly   +3 more sources

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