Results 31 to 40 of about 250,265 (247)

In Vivo 3D Imaging of Retinal Neovascularization Using Multimodal Photoacoustic Microscopy and Optical Coherence Tomography Imaging

Journal of Imaging, 2018
The pathological process of neovascularization of the retina plays a critical role in causing vision loss in several diseases, including diabetes, retinal vein occlusion, and sickle cell disease. Retinal neovascularization can lead to vitreous hemorrhage
Van Phuc Nguyen, Yanxiu Li, Michael Aaberg, Wei Zhang, Xueding Wang, Yannis M. Paulus   +5 more
doaj   +1 more source

Vascular cell-adhesion molecule 1 (VCAM-1) regulates JunB-mediated IL-8/CXCL1 expression and pathological neovascularization

Communications Biology, 2023
Vascular adhesion molecules play an important role in various immunological disorders, particularly in cancers. However, little is known regarding the role of these adhesion molecules in proliferative retinopathies.
Geetika Kaur, Deepti Sharma, Shivantika Bisen, Chandra Sekhar Mukhopadhyay, Katherine Gurdziel, Nikhlesh K. Singh   +5 more
doaj   +1 more source

Sphingosine Kinase 2 Modulates Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy. [PDF]

, 2018
Purpose Neovascularization is a major cause of blindness in various ocular diseases. Bioactive sphingosine 1-phosphate (S1P), synthesized by two sphingosine kinases (Sphk1, Sphk2), emerged as a key player in a multitude of cellular processes ...
Koch, Alexander, Devraj, Kavi, Lars-Olof Hattenbach, Vutukuri, Rajkumar, Yannick Schreiber, Huwiler, Andrea, Katrin Schröder, Kavi Devraj, Popp, Rüdiger, Alexander Koch, Martin Stumpf, Pfeilschifter, Josef, Nerea Ferreirós, Andrea Huwiler, Jeanette Eresch, Eresch, Jeanette, Hattenbach, Lars-Olof, Waltraud Pfeilschifter, Rüdiger Popp, Stumpf, Martin, Rajkumar Vutukuri, Ferreirós, Nerea, Pfeilschifter, Waltraud, Josef Pfeilschifter, Schreiber, Yannick, Schröder, Katrin, Schröder K, Pfeilschifter, W., Pfeilschifter W, Popp R, Koch A, Stumpf, M., Huwiler, A., Schreiber Y, Eresch J, Pfeilschifter J, Hattenbach LO, Vutukuri, R., Eresch, J., Pfeilschifter, J., Vutukuri R, Devraj K, Schröder, K., Stumpf M, Popp, R., Koch, A., Schreiber, Y., Ferreirós N, Huwiler A, Ferreiros, N., Hattenbach, L.-O., Devraj, K.   +51 more
core   +2 more sources

Inflammatory retinal and choroidal neovascularization in a case of post-fever immune retinitis

Indian Journal of Ophthalmology. Case Reports, 2021
The development of retinal and choroidal neovascularization in posterior uveitis is attributed to the angio-inflammatory drive with/without ruptures in the retinal pigment epithelium-Bruch's membrane complex.
Pratik Shenoy, Gaurav Mohan Kohli, Priyavrat Bhatia, Alok Sen   +3 more
doaj   +1 more source

Expeditious resolution of disc and iris neovascularization

Indian Journal of Ophthalmology. Case Reports
Intraocular neovascularization is seen commonly as a response to retinal ischemia or less commonly due to inflammation. Inflammatory iris neovascularization responds well to topical steroids, whereas retinal neovascularization associated with uveitic ...
Shreyas Temkar, Geeta Behera, Hemanth Ramachandar, Disha Agarwal, Mary Stephen, Amit Kumar Deb   +5 more
doaj   +1 more source

Therapeutic effect against retinal neovascularization in a mouse model of oxygen-induced retinopathy: bone marrow-derived mesenchymal stem cells versus Conbercept

BMC Ophthalmology, 2020
Background To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy.
Wei Xu, Weijing Cheng, Xiaoyuan Cui, Guoxing Xu   +3 more
doaj   +1 more source

Ref-1 redox activity regulates retinal neovascularization by modulating transcriptional activation of HIF-1α. [PDF]

FASEB J
Retinal neovascularization impairs visual function and is a hallmark of several neovascular eye diseases, including retinopathy of prematurity (ROP) and proliferative diabetic retinopathy (PDR).
Hartman GD, Muniyandi A, Sishtla K, Kpenu EK, Miller WP, Kaplan BA, Kim LA, Liu S, Wan J, Qi X, Boulton ME, Kelley MR, Corson TW.   +12 more
europepmc   +2 more sources

Therapeutic Effects of Fenofibrate Nano-Emulsion Eye Drops on Retinal Vascular Leakage and Neovascularization

Biology, 2021
Macular edema caused by retinal vascular leakage and ocular neovascularization are the leading causes of severe vision loss in diabetic retinopathy (DR) and age-related macular degeneration (AMD) patients.
Li Huang, Wentao Liang, Kelu Zhou, Ronald A. Wassel, Zachary D. Ridge, Jian-Xing Ma, Bing Wang   +6 more
doaj   +1 more source

Results of neovascularization detection on retinal images.

, 2013
Results of neovascularization detection on retinal images.
Benny Chung Ying Zee (497798), Jack Lee (497797), Qing Li (84975)   +2 more
core   +1 more source

Endothelium Expression of Bcl-2 Is Essential for Normal and Pathological Ocular Vascularization.

PLoS ONE, 2015
Bcl-2 is an anti-apoptotic protein with important roles in vascular homeostasis and angiogenesis. Mice globally lacking Bcl-2 (Bcl-2 -/-) are small in stature and succumb to renal failure shortly after weaning as a result of renal hypoplasia/cystic ...
Ismail S Zaitoun, Ryan P Johnson, Nasim Jamali, Reem Almomani, Shoujian Wang, Nader Sheibani, Christine M Sorenson   +6 more
doaj   +1 more source